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Articles selected by Faculty of 1000: CNS gene-expression atlas; finding Cdk1 targets; metabolic labeling C. elegans and Drosophila; allele-specific silencing by RNAi; identifying long-range enhancers

Summary

A selection of evaluations from Faculty of 1000 covering a gene expression atlas of the central nervous system, the identification of Cdk1 targets, metabolic labeling C. elegans and Drosophila, allele-specific silencing by RNAi and identifying human long-range enhancers.

CNS gene-expression atlas

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, Schambra UB, Nowak NJ, Joyner A, Leblanc G, Hatten ME, Heintz N. Nature 2003, 425:917-925.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-12-354.asp#Gong

Finding Cdk1 targets

Targets of the cyclin-dependent kinase Cdk1. Ubersax JA, Woodbury EL, Quang PN, Paraz M, Blethrow JD, Shah K, Shokat KM, Morgan DO. Nature 2003, 425:859-864.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-12-354.asp#Ubersax

Metabolic labeling C. elegans and Drosophila

Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics. Krijgsveld J, Ketting RF, Mahmoudi T, Johansen J, Artal-Sanz M, Verrijzer CP, Plasterk RH, Heck AJ. Nat Biotechnol 2003, 21:927-931.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-12-354.asp#Krijgsveld

Allele-specific silencing by RNAi

Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference. Abdelgany A, Wood M, Beeson D. Hum Mol Genet 2003, 12:2637-2644.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-12-354.asp#Abdelgany

Identifying long-range enhancers

Scanning human gene deserts for long-range enhancers. Nobrega MA, Ovcharenko I, Afzal V, Rubin EM. Science 2003, 302:413.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-12-354.asp#Nobrega

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Articles selected by Faculty of 1000: CNS gene-expression atlas; finding Cdk1 targets; metabolic labeling C. elegans and Drosophila; allele-specific silencing by RNAi; identifying long-range enhancers. Genome Biol 4, 354 (2003). https://doi.org/10.1186/gb-2003-4-12-354

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Keywords

  • Central Nervous System
  • Acetylcholine
  • Bacterial Artificial Chromosome
  • Human Gene
  • Acetylcholine Receptor