Figure 3
From: A new non-linear normalization method for reducing variability in DNA microarray experiments
Relative signal distributions before and after normalization. Relative signals (log-ratios) log(x)-log (v), for oligonucleotide arrays (HIV, top row) and cDNA arrays (glnA, bottom row). One distribution is shown for each microarray before normalization (left) after lowess normalization (centre) and after qspline normalization (right). Control samples are shown in green, treatment samples in red and normal distributions fitted to the median and MAD of all log-ratios in black.