|
Human candidate
|
Mouse candidate
|
Sense gene
|
Antisense gene or homolog
|
|---|
|
Hs.250697
|
Mm.826
|
TC10
|
PIGF
|
|
Hs.211601
|
Mm.4358
|
MAP3K12
|
No protein match
|
|
Hs.2210
|
Mm.10167
|
FLJ22865
|
TRIP3
|
|
Hs.296776
|
Mm.20848
|
RFXANK
|
LOC126382
|
|
Hs.170263
|
Mm.25231
|
TP53BP1
|
No protein match
|
|
Hs.330310
|
Mm.176845
|
KIAA0632
|
G10
|
|
Hs.343244
|
Mm.10698
|
AP1G2
|
No protein match
|
- Seven pairs of mouse and human candidate UniGene clusters that contain clear orthologs are listed. In the first six, the location, coding potential/identity, and pattern of overlap of the sense and antisense RNA species are consistent between the mouse and human candidates. Thus, in the first example, a sub-region of the terminal exon of Ras-like protein overlaps the full terminal exon of a class F phosphatidylinositol glycan (Hs.250697 and Mm.826). In the second example, the 3' UTR of MAPKKK12 is overlapped by a transcript with no protein homologies in both mouse and human; moreover, this non-coding region of overlap is highly conserved at nucleotide level between mouse and human (Hs.211601 and Mm.4358).
