Untranslated regions of mRNAs

Table 3 Examples of 5' UTR sequences with highly stable stem-loop structures

UTR	EMBL	Gene description	UTR length	Stem length	ΔG
5hsa007030	X12949	Ret	963	129	-125.4
5hsa034512	AF274954	PNAS-29	323	95	-71.7
5hsa019215	AF139980	LW-1 (LW-1)	716	72	-66.1
5hsa019416	AF152961	Chromatin-specific transcription elongation factor	291	97	-61.9
5hsa022262	S95936	Transferrin	79	65	-60.1
5hsa000763	U19144	GAGE-3 protein	99	72	-54.6
5hsa022576	AF116649	PRO0566	2,011	72	-51.6

Highly stable structures are defined as those with ΔG ≤ -50 kcal/mol. Free energy was calculated with 'foldrna' program (GCG [53]) on stem-loop elements found with the PatSearch program on human UTRdb [47]. Stem length represents the total number of nucleotides involved in the structure.

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