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Table 3 Examples of 5' UTR sequences with highly stable stem-loop structures

From: Untranslated regions of mRNAs

UTR EMBL Gene description UTR length Stem length ΔG
5hsa007030 X12949 Ret 963 129 -125.4
5hsa034512 AF274954 PNAS-29 323 95 -71.7
5hsa019215 AF139980 LW-1 (LW-1) 716 72 -66.1
5hsa019416 AF152961 Chromatin-specific transcription elongation factor 291 97 -61.9
5hsa022262 S95936 Transferrin 79 65 -60.1
5hsa000763 U19144 GAGE-3 protein 99 72 -54.6
5hsa022576 AF116649 PRO0566 2,011 72 -51.6
  1. Highly stable structures are defined as those with ΔG ≤ -50 kcal/mol. Free energy was calculated with 'foldrna' program (GCG [53]) on stem-loop elements found with the PatSearch program on human UTRdb [47]. Stem length represents the total number of nucleotides involved in the structure.