Chromosomal mapping of the nine human PKC gene loci by FISH to metaphase spreads. (a) Composite karyotype of the nine distinct PKC genes assigned by FISH (in green) to human metaphase spreads (DAPI/PI banding). The PKC gene product label indicates the assignment of the averaged fluorescence peak to the corresponding chromosome band. (b) Ideograms depicting the distribution of fluorescent spots (indicated by vertical bars at the side of the ideograms). Each mark represents the localization of one hybridization spot; n = number of metaphases scored.