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Table 2 Pattern discovery using ROMs (regions of overlapping matches) with maximal score to find binding sites in DNA

From: Evaluation of thresholds for the detection of binding sites for regulatory proteins in Escherichia coliK12 DNA

Regulatory protein

Number of genes in the regulon*

Touched by max

Percent touched by max

Touched by other§

Total percent touched

Not touched**

Without dyads††

ArgR

6

2

33.33

4

100.00

0

0

CRP

54

42

77.78

8

92.59

4

0

FNR

17

10

58.82

0

58.82

2

5

GlpR

4

3

75.00

1

100.00

0

0

IlvY

2

2

100.00

0

100.00

0

0

LexA

8

8

100.00

0

100.00

0

0

MalI

2

2

100.00

0

100.00

0

0

MalT

4

4

100.00

0

100.00

0

0

MelR

2

2

100.00

0

100.00

0

0

NR_I

3

3

100.00

0

100.00

0

0

NarL

6

3

50.00

0

50.00

2

1

PhoB

4

4

100.00

0

100.00

0

0

PurR

12

11

91.67

0

91.67

1

0

TorR

1

1

100.00

0

100.00

0

0

TrpR

5

4

80.00

1

100.00

0

0

TyrR

8

7

87.50

0

87.50

1

0

  1. *The total number of genes in the regulon with a known binding site (in the 400+50 upstream regions). The number of regions where a ROM (region of overlapping matches) with the highest number of matches (max ROM) touches a known binding site. This value expressed as a percentage. §Number of regions where either a ROM or dyad touches a known binding site, but the max ROM does not. The percentage of all upstream regions in which any ROM touches a binding site. **Number of regions with dyads, but no match between known binding sites and ROMs. ††Number of regions with no dyads at all.