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Figure 2 | Genome Biology

Figure 2

From: Using orthologous and paralogous proteins to identify specificity determining residues

Figure 2

Structure of PurR bound to the DNA. Two chains of the dimer are shown semi-transparent in light green and pink. Predicted specificity determinants are shown by space-filling and colored red in the pink chain and green in the light green chain. The ligand () and the DNA are shown in blue. Notice deep penetration of some specificity-determining residues into the DNA and formation of the ligand-binding pocket by most of the others.

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