Figure 5

Specificity of the models as a function of their sensitivity. Scores for physiologic RSS were ranked in ascending order so that the lowest score was ranked 0, the second lowest score was ranked 1, and so on. For each score, the number of physiologic RSS with a lower score is equal to this rank. We used the lowest 5% of scores as test thresholds: ranks 0 through 10 were used for the three 12-RSS models and ranks 0 through 8 were used for the three 23-RSS models. (a) Results for the 12-RSS models; (b) results for the 23-RSS models. The number of physiologic RSS scoring below a given threshold score (Table 5) is given on the x-axis, and the frequency of non-RSS segments in chromosome 8 sequence AC084823 scoring above the threshold is shown on the y-axis. Solid line, RIC; dashed line, WM1; dotted line, WM0.