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Tracking down pathways and molecular interactions

Genome Biology20013:reports2004

https://doi.org/10.1186/gb-2001-3-1-reports2004

  • Received: 19 November 2001
  • Published:

Abstract

The KEGG project, initiated by the Japanese Human Genome Program in 1995, aims to computerize knowledge on molecular interactions among genes and proteins, metabolic pathways, regulatory pathways and molecular assemblies

Keywords

  • Molecular Interaction
  • Regulatory Pathway
  • Molecular Assembly
  • License Agreement
  • Pathway Diagram

Content

The KEGG project, initiated by the Japanese Human Genome Program in 1995, aims to computerize knowledge on molecular interactions among genes and proteins, metabolic pathways, regulatory pathways and molecular assemblies. The data are presented in graphical diagrams, HTML tables, hierarchical text or Java graphics. The pathway map, for example, covers all known metabolic pathways and some gene regulatory pathways. Each enzyme represented in the diagram is given its standard EC number, which is a useful tag to explore for more information, such as gene data, homologous genes and additional pathways in which the protein is involved. The site contains and maintains genome data such as genome maps and sequences, not only from humans but also from a large variety of species. It also supports several other databases, such as EMBL, PIR and PDB.

Navigation

Reporter's comments

Timeliness

The site is updated daily and some of the information can be received on CD ROM, which is updated weekly.

Best feature

A huge amount of information from the genome project is collected and compared here. The pathway diagrams are particularly useful in understanding the exact action of a particular gene.

Worst feature

Although the site is well presented, it takes some time to get familiar with all the things it can offer.

Related websites

GeneCards provides a wide range of information on genes and their involvement in disease through searching with their approved gene symbol.

Table of links

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