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Table 1 The 39 groups of orthologous C2H2 ZNF genes defined by our analyses

From: Identification of conserved C2H2 zinc-finger gene families in the Bilateria

Gene family

Human

Drosophila

C. elegans

1 Sp

Sp1 (SP:P08047)

Btd (CT35305; SPTR:Q24266)

T22C8.5 (SPTR:Q22678)

 

Sp2 (SP:Q02086)

DSp1 (CT2914; SPTR:Q9U1K4)

Y40B1A.4 (SPTR:Q9XW26)

 

Sp3 (SP:Q02447)

  
 

Sp4 (SP:Q02446)

  

2 Zic

Zic1 (SP:Q15915)

Opa (CT1819; SPTR:P39768)

C47C12.3 (SPTR:Q94178)

 

Zic2 (SP:O95409)

  
 

Zic3 (SP:O60481)

  

3 Ovo

Ovol1 (SP:O14753)

Ovo (CT21113, CT36311; SPTR:P51521)

F34D10.5 (SPTR:Q19996)

 

SPTR:O00110

  
 

SPTR:Q9Y4M0

  

4 Snail

Slug (SP:O43623)

Snail (CT13146; SPTR:P08044)

C55C2.1 (SPTR:O01830)

 

Snai1 (SP:O95863)

Escargot (CT12561; SPTR:P25932)

F43G9.11 (SPTR:Q93721)

 

SnaiP1 (Snai1 pseudogene)

Worniu (CT13175; SPTR:Q9NK88)

 
  

Scratch (CT1817; SPTR:Q24140)

 
  

CT33426 (SPTR:Q9W0P9)

 
  

CT34835 (SPTR:Q9VZK3)

 

5 Gli

Gli/Gli1 (SP:P08151)

Ci (CT6641; SPTR:P19538)

Tra-1 (Y47D3A.6; SPTR:Q9U2C0)

 

Gli2 (SP:P10070)

  
 

Gli3 (SP:P10071)

  

6 Egr/Krox

Egr1/Krox-24 (SP:P18146)

Stripe (CT23724; SPTR:Q24163)

C27C12.2 (SPTR:Q18250)

 

Egr2/Krox-20 (SP:P11161)

 

Y55F3AM.7 (SPTR:Q9N374)

 

Egr3 (SP:Q06889)

  
 

Egr4 (SP:Q05215)

  

7 KLF

EZF/GKLF (SPTR:Q9UNP3)

CT2144 (SPTR:Q9VZN4)

F56F11.3 (SPTR:Q9TZ64)

 

LKLF (SPTR:Q9UKR6)

CT27882 (SPTR:Q9W1W2)

F53F8.1 (SPTR:O62259)

 

UKLF (SP:O75840)

CT14096 (SPTR:Q9VPQ5)

mua1/F54H5.4 (SPTR: P91329)

 

BKLF (SP:P57682)

CT9920 (SPTR:O77251)

 
 

EKLF (SP:Q13351)

  
 

KKLF (SPTR:Q9UIH9)

  
 

ZNF741 (SPTR:O95600)

  
 

NSLP1 (SPTR:Q9Y356)

  
 

BTEB1 (SP:Q13886)

  
 

ZF9/CPBP (SP:Q99612)

  
 

BTEB2/CKLF (SP:Q13887)

  
 

AP-2REP (SPTR:Q9UHZ0)

  
 

TIEG1 (SP:Q13118)

  
 

TIEG2 (SP:O14901)

  

8 Zfh-1

SPTR:O60315

Zfh-1 (CT2773; SPTR:P28166)

F28F9.1 (SPTR:Q94196)

 

NIL-2-A (SP:P37275)

  

9 Zfh-2

ATBF1 (SPTR:Q13719)

Zfh-2 (CT3397; SPTR:P28167)

ZC123.3 (SPTR:O45019)

10 Odd-like

EM:AI126171

Odd (CT12867; SPTR:P23803)

YKC4 (B0280.4; SPTR:P41995)

  

Sob (CT10899; SPTR:Q24571)

C34H3.2 (SPTR:Q9N5X6)

  

Bowl (CT9648, CT37221;

 
  

CT40018, SPTR: Q9VQU9)

 

11 Spalt

HSAL1 (SPTR:Q99881)

Spalt-major (CT20082; SPTR:P39770)

SEM-4 (SPTR:Q17396)

 

HSAL2 (SPTR:Q9Y467)

Spalt-related (CT15643; SPTR:Q24163)

 
 

SALL3 (SPTR:Q9UGH1)

  

12 Disco

Basonuclin (SPTR:Q01954)

Disco (CT27904; SPTR:P23792)

F55C5 (SPTR: Q20815)

 

SPTR:Q9NXV0

CT26340 (SPTR:Q9VXJ5)

 

13 GFI

GFI-1, GFI-1B (SPTR:Q99684)

CT31381 (SPTR:Q9VM77)

F45B8.4 (SPTR:O02265)

14 YY1

TYY1 (SPTR:P25490)

Pho (CT39329; SPTR:O76247)

 
 

SPTR:O15391

CT11601 (SPTR:Q9VSZ3)

 

15 BLIMP-1

BLIMP-1 (SPTR:O95914)

CT16759 (SPTR:Q9VRN4)

F25D7.3 (SPTR:Q93560)

16 Zep

Zep1 (SP:P15822)

Schnurri (CT23537; PIR:A56922)

T05A10.1 (SPTR:Q22190)

 

Zep2 (SP:P31629)

  
 

KBP-1 (SPTR:Q99302)

  

17 IA-1*

IA-1 (SP:Q01101)

CT31935 (SPTR:Q9VH29)

K11G9.4 (SPTR:Q23011)

  

Nerfin-1 (CT33443; SPTR:Q9V3B8)

 

18 Evi-1*

Evi-1 SP:Q03112)

CT29074 (SPTR:Q9VJ55)

R53.3 (A and B) (SPTR:Q22024)

  

CT29650 (SPTR:Q9VJ52)

 

19 SAP61

SAP 61 (SPTR:Q12874)

Noisette (CT7078; SPTR:O46106)

T13H5.4 (SPTR:Q22469)

20 SP62*

SP62 (SP:Q15428)

CT30142 (SPTR:Q9VU15)

F11A10.2 (SPTR:Q19335)

21 Kin-17

KIN-17 (SPTR: O60870)

Kin-17 (CT17834; SPTR:O76926)

Y52B11A.9 (SPTR:Q9XWF2)

22 Hindsight

FinB (SPTR:Q9Y474)

Hindsight

 
 

RREB-1 (SP:Q92766)

(CT11247; PIR:T13594)

 

23 MTF

MTF-1 (SPTR:Q14872)

CT12477 (SPTR:Q9NFS1)

 

24 ZNF207*

ZNF207 (SP:O43670)

CT39886 (SPTR:Q9VJI6)

B0035.1 (SPTR:Q93156)

25 ZNF277*

ZNF277 (SP:Q9NRM2)

CT27874 (SPTR:Q9W1V7)

F46B6.7 (SPTR:Q20448)

26 Fez

SPTR:Q9NWB9

CT22557 (SPTR:Q9VQ56)

Y38H8A.5 (SPTR:O62425)

27 OAZ*

OAZ (SPTR:Q9NZ13)

CT33481 (SPTR:Q9V724)

 

28 Zfam 1*

HSPC038 (SPTR:Q9Y5V0)

CT35941 (SPTR:Q9VUU8)

C01F6.9 (SPTR:O62023)

  

CT40578 (SPTR:Q9VUU7)

 

29 Zfam 2*

SPTR:Q9NWA7

CT27270 (SPTR:Q9W3S1)

F13H6.1 (SPTR:O16350)

30 Zfam 3*

SPTR:Q9NTN4

CT15069 (SPTR:Q9VCS3)

 

31 Zfam 4*

EM:AI907237

CT17352 (SPTR:Q9U9A8)

Lin29 (SPTR:Q9N6B5)

32 Zfam 5*

EM:Z64553

CT21013 (SPTR:Q9VX08)

C16A3.4 (SPTR:Q18036)

33 Zfam 6*

Ptg-12 (EM:X97303)

CT36542 (SPTR:Q9VZF0)

ZK686.4 (SP:P34670)

34 Zfam 7*

EM:AC005606

CT31867 (SPTR:Q9W149)

 

35 Zfam 8*

EM:AK000711

CT4004 (SPTR:Q9V9Z6)

 

36 Zfam 9*

EM:HS626B19

CT32584 (SPTR:Q9VRV0)

 

37 Zfam 10*

Br140/BRPF1 (SP:P55201)

CT5659 (SPTR:Q9V4J4)

 
 

Br140-like (SP:O95696)

  

38 Zfam 11*

EM:AI077328

CT32574 (SPTR:Q9VRQ6)

 

39 Zfam 12*

HPCMF (SPTR:Q9P0J7)

CT32121 (SPTR:Q9VHI5)

 
  1. *Families we believe not to have been defined previously. Human genes are identified by gene name and, where names have not yet been given, by database accession number. Drosophila sequences are identified by gene name and corresponding Gadfly protein symbol in brackets [14], or just by symbol where no name has been ascribed. C. elegans sequences are identified by name where possible and by coding sequence identifier [15]. All sequences are also identified by accession number: where possible these are SWISSPROT TREMBL accession numbers (designated SPTR). In a few cases only SWISSPROT accession numbers (designated SP) could be identified. For a minority of human genes no protein database entries have been made. These derive from EST or genomic sequences and the corresponding EMBL nucleotide database accession number (designated EM) is given.
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