Figure 4

Sequence alignment of the conserved motif in Scc2, Chk1 and Pkh1, which includes the PROSITE serine/threonine (S/T) protein kinase motif. In the alignment the conserved residues of the motif identified using Teiresias are in red and additional conserved positions are in green. The residues that coincide with the S/T kinase motif are outlined with a box. The number before each motif indicates the position of the first residue within the complete sequence. The PROSITE S/T kinase motif is shown beneath the alignment. The alternative residues are shown in squared brackets; X denotes any residue; the active-site aspartic acid is in blue.