Table 1 Aligned sequences homologous to molecular beacons E8/E9 and E9/E10

(a) Beacon E8/E9 sequence

1

Human SHMT-ps1

CCGCACGATCTTCTACAG/GAAAGGAGGGC

2

Chimpanzee SHMT-ps1

CCGCACGATCCTCTACAG/GAAAGGAGTGC

3

Gorilla SHMT-ps1

CCGCACGATCTTCTACAG/GAAAGGAGGGT

4

Orangutan SHMT-ps1

CCGCACGATCCTCTACAG/GAAAGGAGGGC

5

Gibbon SHMT-ps1

CCGCACGATCTTCTACAG/GAAAGGAGGGT

6

Macaque SHMT-ps-1

AGCCGGCATGATCTACGG/GAAAGGAGTGC

7

Baboon SHMT-ps1

AGCCGGCATGATCTACGG/GAAAGGAGTGC

8

Capuchin SHMT-ps1

CCGCACGATCTCCTACAG/GAAAGGAGGGC

9

Spider monkey SHMT-ps1

CCGCACGATCTCCTACAG/GAAAGGAGGGC

10

Tamarin SHMT-ps1

CGGCACGATCTTCTACAG/GAAAGGAGGGC

11

Human SHMT-cyt cDNA

TGGCATGATCTTCTACAG/GAAAGGAGBGA

12

Rabbit SHMT-cyt cDNA

CGGCATGATCTTCTACAG/GAGAGGAGTGC

13

Sheep SHMT-cyt cDNA

CGGCATGATCTTCTACAG/GAAGGGAGTGC

(b) Beacon E9/E10 sequence

1

Human SHMT-ps1

CACAACCACACCATTGCTG/GGGTTGCTG

2

Chimpanzee SHMT-ps1

CACAACCACGCCACTGCTG/GGGTTGCTG

3

Gorilla SHMT-ps1

CACAACCACACCATTGTTG/GGGTTGCTG

4

Orangutan SHMT-ps1

CACAACCACACCATTGCTG/GGGTTGCTG

5

Gibbon SHMT-ps1

CACAACCACACCATTGTTG/GGGTAGCTG

6

Macaque SHMT-ps-1

CACAACCATGCCATTGCTG/GGGTTGCTG

7

Baboon SHMT-ps1

CACAACCATGCTATTGCTG/GGGTTGCTG

8

Capuchin SHMT-ps1

CACAACCACACCATTGTTG/GGGTTGCTG

9

Spider monkey SHMT-ps1

CACAACCACACCATTGTTG/GGGTAGCTG

10

Tamarin SHMT-ps1

CACAACCAAACCAATGCTG/GGGTTTCTG

11

Human SHMT-cyt cDNA

CACAACCACGCCATTGCTG/GGGTTGCTG

12

Rabbit SHMT-cyt cDNA

CACAACCACGCCATCGCAG/GGGTGGCCG

13

Sheep SHMT-cyt cDNA

CACAACCACGCCATTGCTG/GGGTCGCGG