From: The sequence of human chromosome 21 and implications for research into Down syndrome
 |  | Chromosome | Exon |
---|---|---|---|
Gene | Functional class | 21 ORFs | model |
 |  | orf 20 |  |
 |  | orf 21 |  |
 |  | orf 22 |  |
ANKRD3 | Ankyrin kinase | Â | Â |
ZNF298 | Zinc finger | orf 25 | Â |
ZNF295 | Zinc finger | Â | Â |
UMODL1 | Uromodulin | Â | Pred46 |
ABCG1 * | ATP-binding casette transporter | Â | Â |
TFF3 * | Intestinal trefoil | Â | Â |
TFF2 | Spasmolytic peptide | Â | Â |
TFF1 | Estrogen-induced | Â | Â |
TMPRSS3 | Membrane serine protease | Â | Â |
UBASH3A | SH3 domain | Â | Â |
TSGA2 * | Testis-specific | Â | Â |
SLC37A1 | Glycerol 3-phosphate permease | Â | Â |
PDE9A | Cyclic phosphodiesterase | Â | Â |
WDR4 | WD repeats | Â | Â |
NDUFV3 | NADH-ubiquinone oxoreductase subunit | Â | |
PKNOX1 * | Homeobox | Â | Â |
CBS * | Cystathionine ß synthetase |  |  |
U2AF1 | Splicing factor | Â | Â |
CYRA * | Alpha-crystallin | Â | Â |
HSF2BP | Heat shock transcription factor binding | Â | |
 |  |  | Pred47 |
 |  |  | Pred48 |
SNF1LK * | KID2 kinase | Â | Â |
 |  |  | Pred49 |
 |  |  | Pred50 |
 |  |  | Pred51 |
H2BFS | Histone | Â | Â |
KIAAD179 | Â | Â | Â |