Table 3 Human chromosome 21 centromere-proximal genes
From: The sequence of human chromosome 21 and implications for research into Down syndrome
(a) Genes proximal to APP | (b) Genes from APP to SOD1 | ||
|---|---|---|---|
Gene | Classification | Gene | Classification |
Pred 65 | Zn finger | APP | Â |
Pred 3 | Keratinocyte growth factor | Pred24 | Â |
Pred 4 | Similar to KIAA1074 | ADAMTS1 | Metalloproteinase |
orf15 | EST | ADAMTS5 | Metalloproteinase |
Pred5 | Lipase | Pred25 | Exon |
RBM11 | RNA binding | Pred26 | Exon |
Pred6 | Exon | orf23 | EST |
STCH | Stress protein | Pred27 | Exon |
SAMSN-1 | Similar to KIAA0790 | Pred28 | Methyltransferase |
NRIP1 | Nuclear factor | ZNF294 | Zinc finger |
USP28 | Ubiquitin protease | orf6 | EST |
orf34 | EST | USP16 | Ubiquitin protease |
orf35 | EST | CCT8 | T-complex subunit |
orf36 | EST | orf7 | Exon |
orf37 | EST | Bach1 | Transcription factor |
CXADR | Viral receptor | orf12 | EST |
BTG3 | Cell cycle control | orf8 | EST |
YG81 | CDNA | GRIK1 | Glutamate receptor |
orf39 | EST | Orf41 | EST |
Pred12 | Mannose receptor | orf9 | EST |
PRSS7 | Enterokinase | CLDN17 | Claudin receptor |
orf40 | EST | CLDN8 | Claudin receptor |
NCAM2 | Neural adhesion | Pred29 | Exon |
Pred15 | Exon | Pred30 | Exon |
Pred16 | EST | TIAM1 | Lymphoma metastasis |
orf53 | EST | Pred 31 | Exon |
orf42 | EST | SOD1 | Â |
Pred21 | EST | Â | Â |
Red22 | tRNA synthetase | Â | Â |
orf43 | Junction adhesion | Â | Â |
ATP5A | ATPase factor | Â | Â |
GABPA | Transcription factor | Â | Â |