Figure 3
From: Exclusion of EDNRB and KIT as the basis for white spotting in Border Collies
Segregation of EDNRB compared with the segregation of the white spotting phenotype. Genomic DNA digested with PvuII was probed with a radioactively labeled fragment of EDNRB DNA which detected a PvuII restriction fragment length polymorphism (RFLP) between the Border Collie and Newfoundland grandparents. BC, DNA from the Border Collie grandparent; N, DNA from the Newfoundland grandparent. F1, DNA from the first generation hybrids of the Newfoundland × Border Collie cross; F2, DNA from the progeny of intercrosses between the F1 hybrids; s, white spotted; ns, not white spotted. The presumed genotypes for the EDNRB locus are shown below the lanes.