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Call for paper: Long-Read sequencing

Guest Editors: Barbara Wold and Kin Fai Au

Genome Biology is currently inviting submissions for the upcoming special issue on Long-Read Sequencing.

The special issue, which is planned for second half of 2021, is guest edited by Prof. Barbara Wold at California Institute of Technology and Prof. Kin Fai Au at The Ohio State University

Long-read sequencing technologies provide unprecedented opportunities to solve many complex biomedical problems, especially for those unsolved by short-read sequencing. Their long read lengths offer unambiguous mappability for reliable identification of genomic events and are also informative for long-range analyses, such as haplotyping and genome assembly. In addition, the long-read techniques, PacBio and Oxford Nanopore Technologies sequence single molecules and can detect canonical nucleotides as well as base modifications. Both experimental and computational method developments are needed to fully utilize long-read sequencing while accounting for their corresponding weakness (e.g. higher error rates). To translate the technological advances into biomedical breakthroughs, other avenues of research are exploring innovative applications of long-read sequencing to significant biomedical contexts. With a special issue, Genome Biology will highlight these advances in applications and methods of long-read sequencing in related areas. For more information visit our website: .

The special issue will accept Research, Method, Short Report and Database manuscript submissions presenting outstanding contributions that highlight the new findings in the field by applications of long-read sequencing technologies, including (but not limited to) in the areas of:




-Cancer Genomics

-Metagenomics and meta-transcriptomics

-Disease Genomics

Submission deadline: May 1st 2021

Please use the online submission system and indicate in your covering letter that you would like the manuscript to be considered for the ‘Long-Read Sequencing’ special issue. If you would like to inquire about the suitability of a manuscript for consideration, please email a pre-submission inquiry to

Barbara Cheifet
Chief Editor, Genome Biology

Barbara Wold and Kin Fai Au
Guest Editors