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  4. With the recent flood of genomic data many researchers have seen their work become more and more quantitative in nature, and found choice of the appropriate statistical analyses is not only essential but also ...

    Authors: I King Jordan
    Citation: Genome Biology 2001 2:reports2002
    Content type: Web report Published on:

  5. The Spt4, Spt5, and Spt6 proteins are conserved eukaryotic transcription-elongation factors. Recent studies have provided the first evidence that they are generally required in multicellular eukaryotes, includ...

    Authors: Fred Winston
    Citation: Genome Biology 2001 2:reviews1006.1
    Content type: Minireview Published on:

  7. Ever since DNA microarrays were first applied to the quantitation of RNA levels, there has been considerable interest in generating a protein homolog that can be used to assay cellular protein expression. A re...

    Authors: Ian M Tomlinson and Lucy J Holt
    Citation: Genome Biology 2001 2:reviews1004.1
    Content type: Minireview Published on:

  8. Expression arrays have been used to detect mRNAs regulated during sporulation in two strains of Saccharomyces cerevisiae.

    Authors: Rachel Brem
    Citation: Genome Biology 2001 2:reports0003
    Content type: Paper report Published on:

  9. Caenorhabditis elegans populations in which each gene on chromosome I is blocked in turn by RNAi have been grown and phenotypically screened.

    Authors: Rachel Brem
    Citation: Genome Biology 2001 2:reports0002
    Content type: Paper report Published on:

  16. Programmed DNA-reorganization and DNA-elimination events take place frequently during cellular differentiation. An extreme form of such processes, involving DNA reorganization, DNA elimination and DNA fragment...

    Authors: Franziska Jönsson, Günther Steinbrück and Hans J Lipps
    Citation: Genome Biology 2001 2:research0005.1
    Content type: Research Published on:

  18. We have developed and tested a method for printing protein microarrays and using these microarrays in a comparative fluorescence assay to measure the abundance of many specific proteins in complex solutions. A...

    Authors: Brian B Haab, Maitreya J Dunham and Patrick O Brown
    Citation: Genome Biology 2001 2:research0004.1
    Content type: Research Published on:

  31. Replicative DNA polymerases are essential for the replication of the genomes of all living organisms. On the basis of sequence similarities they can be classified into three types. Type A polymerases are homol...

    Authors: M Mar Albà
    Citation: Genome Biology 2001 2:reviews3002.1
    Content type: Protein family review Published on:

  35. We propose a new method for supervised learning from gene expression data. We call it 'tree harvesting'. This technique starts with a hierarchical clustering of genes, then models the outcome variable as a sum...

    Authors: Trevor Hastie, Robert Tibshirani, David Botstein and Patrick Brown
    Citation: Genome Biology 2001 2:research0003.1
    Content type: Research Published on:

  37. Ring-type polymerases consist of a DNA polymerase, a ring-shaped sliding clamp protein and a clamp-loading complex. Sliding clamp proteins are found in all organisms and are called proliferating cell nuclear a...

    Authors: Irina Bruck and Mike O'Donnell
    Citation: Genome Biology 2001 2:reviews3001.1
    Content type: Protein family review Published on:

  38. The mechanism by which the plant reserves some cells as pluripotent stem cells while partitioning others into differentiated leaf tissue is fundamental to plant development. New work in Arabidopsis elucidates the...

    Authors: M Kathryn Barton
    Citation: Genome Biology 2001 2:reviews1002.1
    Content type: Minireview Published on:

  47. To assess how automatic function assignment will contribute to genome annotation in the next five years, we have performed an analysis of 31 available genome sequences. An emerging pattern is that function can...

    Authors: Ioannis Iliopoulos, Sophia Tsoka, Miguel A Andrade, Paul Janssen, Benjamin Audit, Anna Tramontano, Alfonso Valencia, Christophe Leroy, Chris Sander and Christos A Ouzounis
    Citation: Genome Biology 2000 2:interactions0001.1
    Content type: Open letter Published on:

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Genome Biology

ISSN: 1474-760X

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