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Erratum to: Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor
Genome Biology volume 17, Article number: 119 (2016)
In the study [1] a gel depicted in Fig. 2a was labelled in a way which suggests that the sample comes from a Klf3 −/− knockout mouse. In fact, this sample comes from a Klf3 −/− ,Klf8 genetrap double mutant animal. The Klf8 genotype was not indicated as authors felt that it was not relevant for the conclusions of this paper; however, all authors now acknowledge that this information should have been included. Importantly, an equivalent result from single Klf3 −/− knockout mice is included and confirmed in the RNA-seq results presented in Figure 6 of the original article [1].
All other data described in the article were obtained from the Klf3 −/− single knockout mice, and as such the conclusions of the article remain unchanged. It is also critical to note that all other results in the article could not have been obtained from the double mutant mice, because Klf3,Klf8 deficient animals die in utero (as reported by the authors in [2]).
Figure 2 with the correct legend is published in this Erratum.
The authors apologize for this omission and any confusion and inconvenience it may have caused.
References
Mak KS, Burdach J, Norton LJ, Pearson RCM, Crossley M, Funnell APW. Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific 35 transcription factor. Genome Biol. 2014;15:R58.
Funnell APW, Mak KS, Twine NA, Pelka GJ, Norton LJ, Radziewic T, et al. Generation of Mice Deficient in both KLF3/BKLF and KLF8 Reveals a Genetic Interaction and a Role for These Factors in Embryonic Globin Gene Silencing. Mol Cell Biol. 2013;33(15):2976–87.
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The online version of the original article can be found under doi:10.1186/gb-2014-15-4-r58.
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Mak, K.S., Burdach, J., Norton, L.J. et al. Erratum to: Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor. Genome Biol 17, 119 (2016). https://doi.org/10.1186/s13059-016-0977-1
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DOI: https://doi.org/10.1186/s13059-016-0977-1