Correction: Closing gaps in the human genome using sequencing by synthesis

  • Manuel Garber1,

    Affiliated with

    • Michael C Zody1, 2,

      Affiliated with

      • Harindra C Arachchi1,

        Affiliated with

        • Aaron Berlin1,

          Affiliated with

          • Sante Gnerre1,

            Affiliated with

            • Lisa M Green1,

              Affiliated with

              • Niall Lennon1 and

                Affiliated with

                • Chad Nusbaum1Email author

                  Affiliated with

                  Genome Biology201112:403

                  DOI: 10.1186/gb-2011-12-4-403

                  Published: 19 April 2011


                  After publication of this Method [1], we noted errors to the legend of Figure 1. The labelling of the line representing the 454 reads and the line representing the small insert library reads was inverted (please see Figure 1 below, a corrected version of Figure 1).
                  Figure 1

                  Coverage of gap regions. Sequence coverage of the gap regions on human chromosome 15 is shown for gaps at (a) 24 Mb, (b) 25 Mb and (c) 96 Mb. The x-axis indicates base position in the local region containing each gap. The y-axis shows sequence coverage obtained in 454 reads (blue line) and small insert library reads (red line). Coverage was computed as the average in 10-base non-overlapping windows. Arrows indicate primers used to amplify the amplicons sequenced, color coded in pairs. Bars at top indicate bases present in the Celera (dark gray) and NCBI build 36 (light gray) assemblies.

                  Authors’ Affiliations

                  Genome Sequencing and Analysis Program, Broad Institute of MIT and Harvard
                  Department of Medical Biochemistry and Microbiology, Uppsala University


                  1. Garber M, Zody MC, Arachchi HM, Berlin A, Gnerre S, Green LM, Lennon N, Nusbaum C: Closing gaps in the human genome using sequencing by synthesis. Genome Biology 2009, 10:R60.PubMedView Article


                  © BioMed Central Ltd 2011