%PDF-1.3
%
1 0 obj
<>
endobj
2 0 obj
<>stream
Single cell,RNA-seq,Tissue dissociation,Gene expression,Quality control,Breast cancer,Ovarian cancer,Tumor microenvironment
Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version)
application/pdf
10.1186/s13059-019-1830-0
Genome Biology
Genome Biology, 2019, doi:10.1186/s13059-019-1830-0
Single cell
RNA-seq
Tissue dissociation
Gene expression
Quality control
Breast cancer
Ovarian cancer
Tumor microenvironment
Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses
Ciara H. O’Flanagan
Kieran R. Campbell
Allen W. Zhang
Farhia Kabeer
Jamie L. P. Lim
Justina Biele
Peter Eirew
Daniel Lai
Andrew McPherson
Esther Kong
Cherie Bates
Kelly Borkowski
Matt Wiens
Brittany Hewitson
James Hopkins
Jenifer Pham
Nicholas Ceglia
Richard Moore
Andrew J. Mungall
Jessica N. McAlpine
Sohrab P. Shah
Samuel Aparicio
2019-10-17T10:50:53+02:00
2019-10-17T10:50:53+02:00
2019-10-16T04:00:53+08:00
Arbortext Advanced Print Publisher 9.1.440/W Unicode
uuid:bd976f96-eef4-4995-aaf4-fff0ed71b40b
uuid:ea982438-fbc9-4a8f-a4c6-cfb1eeb7938d
default
1
converted
uuid:bd976f96-eef4-4995-aaf4-fff0ed71b40b
converted to PDF/A-2b
pdfToolbox
2019-10-16T04:23:23+08:00
2
B
Samuel Aparicio
http://orcid.org/0000-0002-0487-9599
Springer Nature ORCID Schema
http://springernature.com/ns/xmpExtensions/2.0/
sn
authorInfo
Bag AuthorInformation
external
Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.
editorInfo
Bag EditorInformation
external
Editor information: contains the name of each editor and his/her ORCID identifier.
seriesEditorInfo
Bag SeriesEditorInformation
external
Series editor information: contains the name of each series editor and his/her ORCID identifier.
AuthorInformation
http://springernature.com/ns/xmpExtensions/2.0/authorInfo/
author
Specifies the types of author information: name and ORCID of an author.
name
Text
Gives the name of an author.
orcid
URI
Gives the ORCID of an author.
EditorInformation
http://springernature.com/ns/xmpExtensions/2.0/editorInfo/
editor
Specifies the types of editor information: name and ORCID of an editor.
name
Text
Gives the name of an editor.
orcid
URI
Gives the ORCID of an editor.
SeriesEditorInformation
http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/
seriesEditor
Specifies the types of series editor information: name and ORCID of a series editor.
name
Text
Gives the name of a series editor.
orcid
URI
Gives the ORCID of a series editor.
http://ns.adobe.com/pdf/1.3/
pdf
Adobe PDF Schema
internal
A name object indicating whether the document has been modified to include trapping information
Trapped
Text
http://ns.adobe.com/xap/1.0/mm/
xmpMM
XMP Media Management Schema
internal
UUID based identifier for specific incarnation of a document
InstanceID
URI
internal
The common identifier for all versions and renditions of a document.
OriginalDocumentID
URI
internal
A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original.
DerivedFrom
ResourceRef
Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced.
http://ns.adobe.com/xap/1.0/sType/Part#
stPart
Part
http://ns.adobe.com/xap/1.0/t/pg/
xmpTPg
XMP Paged-Text
internal
A structure containing the characteristics of a font used in a document
Fonts
Bag Font
internal
XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents).
PlateNames
Seq Text
A structure containing the characteristics of a font used in a document.
http://ns.adobe.com/xap/1.0/sType/Font#
stFnt
Font
http://ns.adobe.com/pdfx/1.3/
pdfx
PDF/X ID Schema
internal
ID of PDF/X standard
GTS_PDFXVersion
Text
internal
Conformance level of PDF/X standard
GTS_PDFXConformance
Text
internal
Company creating the PDF
Company
Text
internal
Date when document was last modified
SourceModified
Text
http://www.aiim.org/pdfa/ns/id/
pdfaid
PDF/A ID Schema
internal
Part of PDF/A standard
part
Integer
internal
Amendment of PDF/A standard
amd
Text
internal
Conformance level of PDF/A standard
conformance
Text
endstream
endobj
3 0 obj
<>stream
xYr)pI01TWlbGR*(( Az<>bg@ $Em첩!f{ɻE&,wE&NUVfT6vLZuIVi8NI5m>sϠ'ee+
X5<τU{ic&Y=)4.RYxf
.
.3\Z%*˅ea-T/1xP8
Q ݠtnxq%& G}soN@B
!
*4״|QV"nYQp` !5{.P$Fi$1ČHA(\ydBD`T1cH"1-@SCfZ @A3X qqVwxc E
x±]JeQ%5)Jj٢F)˙pbnWޓeETVbK\ZVHZXMp`+$Y
Ρz+ k Z *
\74nxzmJZ{FOTu3ɞ,^
j7}y5
.$g`dϮ5 Ł-^ȳ?%":l'k7$v[;á/Q2DB!㽹ew1ph֮P~11*1
]$@yvtXhYzƹM}$3 x$H%qwAgw90uL%j{#OQO7{`6OaY-)C+ۖ"72e ED
j+0G{M9jKGe4wg-.ߣE]\Wg_Invt9 1GD.`KO
ɐDW-Hx")QO=*d%cG,>3sC'h$igsn]:yIQ)8uPѡh@/(W(Kn̽hs6,~3 Uo'UE{
/+2,R7b`믜ӥ)ޒaLoo*dVΗ<졥3|-#+G6#N_G$eO #;f}(}ah(5PA#$謁z*\$,kHx ߲K=>
|ٗCkTb^c7q.C8].`GM(m6^Bɭ@ p(} "z=[+(bժĪ)p3:`珆4r$At r:A>|z|cWàRI1]E$3^@9h|{WBL!VJZBY&tqsi,
a A˸3:^_P TPP؛Y89rh
=?-q
U0#y&m9L0Otrc2\DZl?GSj\;+TՐIܴ$>vSOitHxy{.;_>!}z1|?`~An`/ʚ*ikaEG₋Ob6Ͱ\~X#'8dbz_b0{7r# u7i ~px[)H0::+㈹G0Ƴ%hA~k:)p rkJ+7=DŽAA6|"7*1ņ?0~IA^
xZJ;3u GlC@0yidkOo0t%S+IjCwp??g}Gy"R}PƘqrӚ^StڄF8&~-n4BwKzM^\/aQ
L7ƗW\-Bk{%;;)N1[^