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A report of the Molecular Genetics of Model Legumes meeting, John Innes Centre, Norwich, 24-28 June, 2000.
Profiling of gene expression in bacteria is now being used to uncover unknown genes expressed in particular genetic backgrounds or environmental conditions. Obtaining the best possible information from the exp...
The genetic and molecular analysis of circadian timekeeping mechanisms has accelerated as a result of the increasing volume of genomic markers and nucleotide sequence information. Completion of whole genome se...
A minimally redundant set of 15,000 mouse cDNAs derived from early and mid-gestation has been used to analyze global patterns of gene expression in the placenta and embryo.
SignalP provides a resource for the prediction of signal peptide cleavage sites in proteins.
The GRAIL server is one of the many internet resources for predicting genes in uncharacterized genomic DNA.
EMOTIF search is one of a set of four integrated bioinformatics resources at Stanford University devoted to constructing and searching for motifs in protein sequences.
The ExPASy biochemical pathways database provides online access to the biochemical pathways index of Boehringer Mannheim.
Online Mendelian Inheritance in Man is a database of human genes and genetic disorders.
The GeneCards website provides a convenient and integrated interface to a variety of information about human genes.
Genome structure confirms the chastity of some ancient asexuals.
Analysis of highly metastatic melanoma cells using oligonucleotide arrays has identified genes regulating tumor invasiveness.
Matrix methods have been used to find dominant temporal patterns in gene expression data.
The genes involved in the assembly and function of the polar flagellum of Vibrio parahaemolyticus have been analyzed systematically by mutagenesis, DNA sequencing and transcriptional studies.
A new bacterial alternative to the yeast two-hybrid system and phage display for detecting protein-protein and protein-DNA interactions is described.
A report from the Cold Spring Harbor Laboratory 2000 conference on Retroviruses, Cold Spring Harbor, May 23-28, 2000.
A series of reports - and extracts of reports - from the Freedom of Information Conference, 6-7 July, 2000, New York Academy of Medicine. The conference was sponsored by BioMed Central, to promote debate about...
A concurrence of genomic, reverse genetic and biochemical approaches has cracked the decade-long enigma concerning the identity of the transcription factors that control gene expression at the G2/M transition ...
Transcriptional analysis of all the genes expressed by breast tumors has provided the first steps towards defining a molecular signature for the disease, and might ultimately make conventional diagnostic techn...
Genome-wide measures of DNA strand composition have been used to find archaeal DNA replication origins. Archaea seem to replicate using a single origin (as do eubacteria) even though archaeal replication facto...
The recently published genomic sequence of Xylella fastidiosa is the first for a free-living plant pathogen and provides clues to mechanisms of pathogenesis and survival in insect vectors. The sequence data shoul...
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