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Uracil DNA glycosylases (UDGs) are major repair enzymes that protect DNA from mutational damage caused by uracil incorporated as a result of a polymerase error or deamination of cytosine. Four distinct familie...
Potassium channels, tetrameric integral membrane proteins that form aqueous pores through which K+ can flow, are found in virtually all organisms; the genomes of humans, Drosophila, and Caenorhabditis elegans con...
A report on the 'Nuclear architecture and control of gene expression' minisymposium at the first meeting of the European Life Scientists Organisation (ELSO), Geneva, Switzerland, September 2-6, 2000.
A report of the Molecular Genetics of Model Legumes meeting, John Innes Centre, Norwich, 24-28 June, 2000.
Profiling of gene expression in bacteria is now being used to uncover unknown genes expressed in particular genetic backgrounds or environmental conditions. Obtaining the best possible information from the exp...
The genetic and molecular analysis of circadian timekeeping mechanisms has accelerated as a result of the increasing volume of genomic markers and nucleotide sequence information. Completion of whole genome se...
A minimally redundant set of 15,000 mouse cDNAs derived from early and mid-gestation has been used to analyze global patterns of gene expression in the placenta and embryo.
SignalP provides a resource for the prediction of signal peptide cleavage sites in proteins.
The GRAIL server is one of the many internet resources for predicting genes in uncharacterized genomic DNA.
EMOTIF search is one of a set of four integrated bioinformatics resources at Stanford University devoted to constructing and searching for motifs in protein sequences.
The ExPASy biochemical pathways database provides online access to the biochemical pathways index of Boehringer Mannheim.
Online Mendelian Inheritance in Man is a database of human genes and genetic disorders.
The GeneCards website provides a convenient and integrated interface to a variety of information about human genes.
Genome structure confirms the chastity of some ancient asexuals.
Analysis of highly metastatic melanoma cells using oligonucleotide arrays has identified genes regulating tumor invasiveness.
Matrix methods have been used to find dominant temporal patterns in gene expression data.
The genes involved in the assembly and function of the polar flagellum of Vibrio parahaemolyticus have been analyzed systematically by mutagenesis, DNA sequencing and transcriptional studies.
A new bacterial alternative to the yeast two-hybrid system and phage display for detecting protein-protein and protein-DNA interactions is described.
A series of reports - and extracts of reports - from the Freedom of Information Conference, 6-7 July, 2000, New York Academy of Medicine. The conference was sponsored by BioMed Central, to promote debate about...
Transcriptional analysis of all the genes expressed by breast tumors has provided the first steps towards defining a molecular signature for the disease, and might ultimately make conventional diagnostic techn...
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