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  1. For most vertebrate organs and tissues, the majority of development occurs during embryogenesis, and postnatal changes are primarily concerned with growth. The central nervous system is unusual in that a consi...

    Authors: M Clinton, J Manson, D McBride and G Miele
    Citation: Genome Biology 2000 1:research0005.1
  2. A recent study, comparing the maize SILKY1 gene to its well-characterized homolog APETALA3 from Arabidopsis, has provided some of the first evidence pointing to conservation of homeotic gene function between mono...

    Authors: Vivian F Irish
    Citation: Genome Biology 2000 1:reviews1015.1
  3. Using DNA microarrays, 381 genes have been found to be induced in response to unfolded proteins. The identity of the previously characterized 208 of these, and further experiments, have revealed new details on...

    Authors: Ardythe A McCracken and Jeffrey L Brodsky
    Citation: Genome Biology 2000 1:reviews1013.1
  4. The budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe are as different from each other as either is from animals: their ancestors separated about 420 to 330 million years ago....

    Authors: Matthias Sipiczki
    Citation: Genome Biology 2000 1:reviews1011.1
  5. Several studies are starting to show the power of DNA microarrays to identify interactions between animal hosts and their pathogens, and have revealed interesting correlations between host responses to differe...

    Authors: Paul Kellam
    Citation: Genome Biology 2000 1:reviews1009.1
  6. Large gene expression studies, such as those conducted using DNA arrays, often provide millions of different pieces of data. To address the problem of analyzing such data, we describe a statistical method, whi...

    Authors: Trevor Hastie, Robert Tibshirani, Michael B Eisen, Ash Alizadeh, Ronald Levy, Louis Staudt, Wing C Chan, David Botstein and Patrick Brown
    Citation: Genome Biology 2000 1:research0003.1
  7. Genomic approaches to the study of the expression of plant genes induced in response to disease and attack are now showing that there is an intimate association between pathogen perception and general stress d...

    Authors: Edward E Farmer
    Citation: Genome Biology 2000 1:reviews1012.1
  8. A comparison of drought tolerance in plants at extreme ends of the evolutionary spectrum is beginning to show the mechanisms involved.

    Authors: Hans J Bohnert
    Citation: Genome Biology 2000 1:reviews1010.1
  9. A meeting report from the 13th Annual Cold Spring Harbor meeting on Genome Sequencing and Biology, May 10-14, 2000. Cold Spring Harbor, New York

    Authors: Pablo D Rabinowicz, Erik Vollbrecht and Bruce May
    Citation: Genome Biology 2000 1:reports4013.1
  10. A report from the conference entitled Genome Based Gene Structure Determination, Hinxton, UK, 1-2 June, 2000, organised by the European Bioinformatics Institute (EBI).

    Authors: Colin Semple
    Citation: Genome Biology 2000 1:reports4012.1
  11. Webcutter provides a free and easy-to-use interface for the analysis of restriction sites in any sequence.

    Authors: Mar Albà
    Citation: Genome Biology 2000 1:reports2048
  12. BoxShade takes sequence alignments and creates an output file in which the alignment is displayed with identical or similar residues shaded in two different tones of gray.

    Authors: Mar Albà
    Citation: Genome Biology 2000 1:reports2047
  13. The existence of several distinct plant signaling pathways regulating changes in gene expression in response to wounding has been demonstrated using cDNA microarray analysis.

    Authors: Thomas Eulgem
    Citation: Genome Biology 2000 1:reports0061
  14. The availability of the complete sequence of the vaccinia virus genome has enabled a comprehensive two-hybrid analysis in yeast of virus protein-protein interactions.

    Authors: Mar Albà
    Citation: Genome Biology 2000 1:reports0059
  15. A key enzyme involved in flavor biogenesis in ripening strawberries has been discovered using customized cDNA microarrays.

    Authors: Philippe Reymond
    Citation: Genome Biology 2000 1:reports0057

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