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  1. The F-box is a protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction. F-box proteins were first characterized as components of SCF ubiquitin-ligase complexes (na...

    Authors: Edward T Kipreos and Michele Pagano
    Citation: Genome Biology 2000 1:reviews3002.1
  2. The recent completion and assembly of the first draft of the human genome, which combines samples from several ethnically diverse males and females, provides preliminary data on the extent of human genetic var...

    Authors: Todd R Disotell
    Citation: Genome Biology 2000 1:comment2004.1
  3. A report on the Eighth Biannual Xenopus Conference, Estes Park, Colorado, August 16-20, 2000.

    Authors: Curtis R Altmann, Esther Bell and Ali H Brivanlou
    Citation: Genome Biology 2000 1:reports4022.1
  4. The Hox complex is an example of a gene cluster created by tandem duplications. Recent findings suggest the Hox complex may be just part of a larger chromosomal assemblage of homeobox-containing genes that exi...

    Authors: Nipam H Patel and Victoria E Prince
    Citation: Genome Biology 2000 1:reviews1027.1
  5. The functional annotation of proteins identified in genome sequencing projects is based on similarities to homologs in the databases. As a result of the possible strategies for divergent evolution, homologous ...

    Authors: John A Gerlt and Patricia C Babbitt
    Citation: Genome Biology 2000 1:reviews0005.1
  6. A report on the 'Host-Pathogen Interactions' minisymposium at the first meeting of the European Life Scientist Organization (ELSO), Geneva, Switzerland, September 2-6, 2000.

    Authors: Robin C May
    Citation: Genome Biology 2000 1:reports4021.1
  7. A report on the sixth biannual FASEB conference on Yeast Chromosome Structure, Replication and Segregation held in Snowmass, Colorado, 19-24 August, 2000.

    Authors: Sally G Pasion, Eliana B Gómez and Susan L Forsburg
    Citation: Genome Biology 2000 1:reports4020.1
  8. A meeting report from the Santa Cruz Developmental Biology Meeting, University of California at Santa Cruz, USA, July 21-25, 2000.

    Authors: Carol Irving and Anna Sharman
    Citation: Genome Biology 2000 1:reports4019.1
  9. The EMBL Nucleotide Sequence Database is a comprehensive database of DNA and RNA sequences and related information traditionally made available in flat-file format. Queries through tools such as SRS (Sequence ...

    Authors: Lichun Wang, Patricia Rodriguez-Tomé, Nicole Redaschi, Phil McNeil, Alan Robinson and Philip Lijnzaad
    Citation: Genome Biology 2000 1:research0010.1
  10. Standard archival sequence databases have not been designed as tools for genome annotation and are far from being optimal for this purpose. We used the database of Clusters of Orthologous Groups of proteins (C...

    Authors: Darren A Natale, Uma T Shankavaram, Michael Y Galperin, Yuri I Wolf, L Aravind and Eugene V Koonin
    Citation: Genome Biology 2000 1:research0009.1
  11. The tumor gene database is a searchable database of information on over 300 known tumor genes. The information is broken down into 'fact' headings for each gene.

    Authors: Igor E Brodsky
    Citation: Genome Biology 2000 1:reports2055
  12. Motor neuron identity and target selection are primarily genetically controlled.

    Authors: Joe Hao
    Citation: Genome Biology 2000 1:reports0075
  13. Analysis of families suffering from total color blindness has revealed one potential cause of the condition - mutations in a gene encoding a α subunit of the retinal cone cGMP-gated ion channel.

    Authors: Gargi Talukder
    Citation: Genome Biology 2000 1:reports0074
  14. Genes expressed during C. elegans germline development have been identified using DNA microarrays.

    Authors: Barry Lubarsky
    Citation: Genome Biology 2000 1:reports0073
  15. Isolated SNARE proteins have been shown to confer only partial specificity on the fusion of artificial liposomes that mimic cellular membranes, modifying the SNARE hypothesis of membrane fusion.

    Authors: Jason B Bock
    Citation: Genome Biology 2000 1:reports0071
  16. The importance of the lens in eye development has been demonstrated using reciprocal transplantations between an eyed surface-dwelling fish and an eyeless cave fish of the same species.

    Authors: Karen Liu
    Citation: Genome Biology 2000 1:reports0070

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