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  1. A report from the minisymposium on regulated secretion at the 39th Annual Meeting of the American Society for Cell Bilogy, Washington DC, December 11-15, 1999

    Authors: Colin Jamora

    Citation: Genome Biology 2000 1:reports402.1

    Content type: Meeting report

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  2. Launched in September 1998, dbSNP is the central repository for data on single-nucleotide polymorphisms (SNPs), the most common form of sequence variation in human populations.

    Authors: Colin Semple

    Citation: Genome Biology 2000 1:reports243

    Content type: Web report

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  3. The availability of complete genomic sequences of Saccharomyces cerevisiae has catalyzed a cultural change in the practice of yeast biology, providing opportunities to develop high throughput techniques to define...

    Authors: Charles Brenner

    Citation: Genome Biology 2000 1:reviews103.1

    Content type: Minireview

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  4. For those working on the actin cytoskeleton, a major theme of the 39th annual meeting of the American Society for Cell Biology [

    Authors: Anne Ridley

    Citation: Genome Biology 2000 1:reviews102.1

    Content type: Minireview

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  5. The key molecules involved in regulating the assembly and function of the mitotic spindle are shared by evolutionarily divergent species. Studies in different model systems are leading to convergent conclusion...

    Authors: Claire E Walczak

    Citation: Genome Biology 2000 1:reviews101.1

    Content type: Minireview

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  6. GeneCalling, a new expression profiling technique, has been used to elucidate regulatory gene networks in plants.

    Authors: Leonore Reiser

    Citation: Genome Biology 2000 1:reports034

    Content type: Paper report

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  7. Serial analysis of gene expression (SAGE) has been used to analyze the complete human 'transcriptome' - the number, identity and level of expression of genes in humans.

    Authors: Hamish Scott

    Citation: Genome Biology 2000 1:reports031

    Content type: Paper report

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  8. Members of the Arabidopsis Genome Initiative, including the European Union Arabidopsis Genome Sequencing Consortium and The Cold Spring Harbor, Washington University in St Louis and PE Biosystems Arabidopsis Sequ...

    Authors: Todd Richmond

    Citation: Genome Biology 2000 1:reports030

    Content type: Paper report

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  9. Members of the Arabidopsis Genome Initiative, primarily from The Institute for Genomic Research, have completed sequencing one of the first two plant chromosomes.

    Authors: Todd Richmond

    Citation: Genome Biology 2000 1:reports029

    Content type: Paper report

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  10. PCR screening five collections of mutagenized Arabidopsis lines to find those that have T-DNA or transposon insertions in 73 members of the R2R3 MYB gene family has identified 47 insertions into 36 genes.

    Authors: Seung Yon Rhee

    Citation: Genome Biology 2000 1:reports025

    Content type: Paper report

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  11. A new noninvasive technique has been developed that successfully measures calcium dynamics in single Arabidopsis guard cells.

    Authors: Kath Carr and Alistair Hetherington

    Citation: Genome Biology 2000 1:reports024

    Content type: Paper report

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  12. The crystal structure of human SRP54M from the signal recognition particle (SRP) reveals a homodimer interaction, which may be a model for the way signal sequences on nascent proteins recognize and activate th...

    Authors: Rachel Brem

    Citation: Genome Biology 2000 1:reports020

    Content type: Paper report

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  13. Systems analysis of the complete genome sequence combined with biochemical information on metabolic pathways has been used to define and elucidate the relationship between genotype and phenotype for Haemophilus i...

    Authors: Mary Wildermuth

    Citation: Genome Biology 2000 1:reports016

    Content type: Paper report

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  14. Differences in responses to bacterial surface lipopolysaccharides (LPSs) are apparent between and within mammalian species. It has been shown in mice that resistance to LPS is caused by defects in the Toll-lik...

    Authors: Irina Smirnova, Alexander Poltorak, Edward KL Chan, Colleen McBride and Bruce Beutler

    Citation: Genome Biology 2000 1:research002.1

    Content type: Research

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  15. The formin family of proteins has been implicated in signaling pathways of cellular morphogenesis in both animals and fungi; in the latter case, at least, they participate in communication between the actin cy...

    Authors: Fatima Cvrcková

    Citation: Genome Biology 2000 1:research001.1

    Content type: Research

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  16. The use of cDNA microarrays for the study and mapping of gene amplifications and deletions on a whole-genome scale provides a comparison of DNA copy numbers in normal and tumor cells at unprecedented resolution.

    Authors: Aude Fahrer

    Citation: Genome Biology 2000 1:reports011

    Content type: Paper report

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  17. The particular interest of David Ussery and his group is in creating 'structural atlases' of genomes from a detailed analysis of variations in DNA structure.

    Authors: Shuba Gopal

    Citation: Genome Biology 2000 1:reports231

    Content type: Web report

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  18. For those interested in DT40, a chick pre-B-cell line proving increasingly popular for use in gene targeting projects, this is a very useful site.

    Authors: Julie Curran

    Citation: Genome Biology 2000 1:reports227

    Content type: Web report

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  19. Several programs to predict sequence and structural features of a protein can be run simultaneously on the PredictProtein server.

    Authors: Mar Albà

    Citation: Genome Biology 2000 1:reports225

    Content type: Web report

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  20. The NetGene2 server uses a neural network combined with a rule-based system to predict intron splice sites in Arabidopsis thaliana, Caenorhabditis elegansand humans.

    Authors: Todd Richmond

    Citation: Genome Biology 2000 1:reports223

    Content type: Web report

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  21. Data are collected from Nature, Science, Cell, and Nature Cell Biologyto form a database and resource for the signaling pathways of human cells.

    Authors: Iain Gilfillan

    Citation: Genome Biology 2000 1:reports221

    Content type: Web report

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  22. This online version of a US Department of Energy publication provides detailed background information about the human genome project.

    Authors: Basil Safwat

    Citation: Genome Biology 2000 1:reports215

    Content type: Web report

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  23. This site has a collection of features dealing with different areas of genetic research, and is an interesting and useful piece of 'popular science'.

    Authors: Basil Safwat

    Citation: Genome Biology 2000 1:reports213

    Content type: Web report

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  24. This comprehensive online biology reference book consists of lists of terms covering an extensive range of biological topics, and is aimed primarily at graduate students.

    Authors: Ines Chyla

    Citation: Genome Biology 2000 1:reports207

    Content type: Web report

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  25. SYFPEITHI, a database of interactions between proteins of the major histocompatibility complex (MHC) and antigenic peptides, contains information on MHC-associated peptide sequences, anchor positions, MHC mole...

    Authors: Christopher J Thorpe

    Citation: Genome Biology 2000 1:reports203

    Content type: Web report

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  26. The first publication of the genomic sequence of an entire human chromosome.

    Authors: Jonathan B Weitzman

    Citation: Genome Biology 2000 1:reports019

    Content type: Paper report

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  27. Plant defense responses are induced by recognition of a conserved epitope of the major protein of the bacterial flagellum. This could represent a general perception mechanism for plants to detect infection by ...

    Authors: William Deakin

    Citation: Genome Biology 2000 1:reports013

    Content type: Paper report

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  28. Bioinformatic analysis has been used to identify gene-fusion events in complete genomes and thus infer protein interactions on the basis of sequence analysis alone.

    Authors: Paul Kellam

    Citation: Genome Biology 2000 1:reports009

    Content type: Paper report

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  29. The isolation of a putative receptor protein for rhizobial nod factors that is located on the surface of legume roots and also has nucleotide hydrolytic properties is described.

    Authors: William Deakin

    Citation: Genome Biology 2000 1:reports007

    Content type: Paper report

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  30. Protein virulence factors can be secreted from bacterial cells using the machinery used to assemble the flagellum.

    Authors: William Deakin

    Citation: Genome Biology 2000 1:reports003

    Content type: Paper report

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  31. YopJ, a virulence factor of Yersinia pseudotuberculosis, can bind to several key intracellular signaling proteins, members of the MAPKK family, preventing their activation and protecting the pathogen from host de...

    Authors: Jonathan B Weitzman

    Citation: Genome Biology 2000 1:reports001

    Content type: Paper report

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