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  1. A large family of G-protein-coupled receptors, with sequence homology to the oncoprotein MAS1, has been shown to be specifically expressed in nociceptive sensory neurons.

    Authors: Maria Östergård
    Citation: Genome Biology 2001 2:reports0048
  2. Predicted extracellular proteins of Bacillus subtilis have been compared with the experimental identification of the extracellular proteome by two-dimensional gel electrophoresis, peptide sequencing and mass spec...

    Authors: Agnieszka M Lichanska
    Citation: Genome Biology 2001 2:reports0047
  3. Transcriptional profiling of 60 human cancer lines has been used to assess chemosensitivity to 232 chemical compounds.

    Authors: Agnieszka M Lichanska
    Citation: Genome Biology 2001 2:reports0046
  4. Genetic evidence supports the recognition and conservation management of African forest and savannah elephants as two distinct species.

    Authors: John C Rockett
    Citation: Genome Biology 2001 2:reports0045
  5. Systematic examination of the gene encoding CYP2B6, a human cytochrome P450, has characterized genetic polymorphisms that might account for its variability in expression and function between individuals.

    Authors: John C Rockett
    Citation: Genome Biology 2001 2:reports0044
  6. Granzymes, a family of serine proteases, are expressed exclusively by cytotoxic T lymphocytes and natural killer (NK) cells, components of the immune system that protect higher organisms against viral infectio...

    Authors: Joseph A Trapani
    Citation: Genome Biology 2001 2:reviews3014.1
  7. All G-protein-coupled receptors (GPCRs) share a common molecular architecture (with seven putative transmembrane segments) and a common signaling mechanism, in that they interact with G proteins (heterotrimeri...

    Authors: Anthony J Harmar
    Citation: Genome Biology 2001 2:reviews3013.1
  8. Gene-expression profiling has yielded important information about simple systems, but complex tissues have not yet been widely profiled. Four recent studies of mammalian skeletal muscles have added to the cata...

    Authors: Richard Hampson and Simon M Hughes
    Citation: Genome Biology 2001 2:reviews1033.1
  9. Symbioses between unicellular and multicellular organisms have contributed significantly to the evolution of life on Earth. As exemplified by several studies of bacterium-insect symbioses, modern genomic techn...

    Authors: Evelyn Zientz, Francisco J Silva and Roy Gross
    Citation: Genome Biology 2001 2:reviews1032.1
  10. Authors: Jonathan B Weitzman
    Citation: Genome Biology 2001 2:spotlight-20011121-01
  11. A report on the International conference on Halophilic Microorganisms, Sevilla, Spain, 23-27 September 2001.

    Authors: Mike Dyall-Smith and Michael Danson
    Citation: Genome Biology 2001 2:reports4033.1
  12. A report on the symposium 'Mycobacteria - new developments' at the 149th meeting of Society for General Microbiology, University of East Anglia, Norwich, UK, 10-13 September 2001.

    Authors: M Jo Colston
    Citation: Genome Biology 2001 2:reports4032.1
  13. Affymetrix oligonucleotide arrays simultaneously measure the abundances of thousands of mRNAs in biological samples. Comparability of array results is necessary for the creation of large-scale gene expression ...

    Authors: Andrew A Hill, Eugene L Brown, Maryann Z Whitley, Greg Tucker-Kellogg, Craig P Hunter and Donna K Slonim
    Citation: Genome Biology 2001 2:research0055.1
  14. Detection of changes in a protein's evolutionary rate may reveal cases of change in that protein's function. We developed and implemented a simple relative rates test in an attempt to assess the rate constancy...

    Authors: I King Jordan, Fyodor A Kondrashov, Igor B Rogozin, Roman L Tatusov, Yuri I Wolf and Eugene V Koonin
    Citation: Genome Biology 2001 2:research0053.1
  15. The biomedical community is rapidly developing new methods of data analysis for microarray experiments, with the goal of establishing new standards to objectively process the massive datasets produced from fun...

    Authors: David M Mutch, Alvin Berger, Robert Mansourian, Andreas Rytz and Matthew-Alan Roberts
    Citation: Genome Biology 2001 2:preprint0009.1
  16. A report on the 2001 Eukaryotic DNA Replication meeting, Cold Spring Harbor Laboratory, New York, 5-9 September 2001.

    Authors: Conrad A Nieduszynski, Anne D Donaldson and J zaJulian Blow
    Citation: Genome Biology 2001 2:reports4030.1
  17. Sequestration of transcription factors in the membrane is emerging as an important mechanism for the regulation of gene expression. A handful of membrane-spanning transcription factors has been previously iden...

    Authors: Joel Zupicich, Steven E Brenner and William C Skarnes
    Citation: Genome Biology 2001 2:research0050.1
  18. Computational predictions are critical for directing the experimental study of protein functions. Therefore it is paradoxical when an apparently erroneous computational prediction seems to be supported by expe...

    Authors: Lakshminarayan M Iyer, L Aravind, Peer Bork, Kay Hofmann, Arcady R Mushegian, Igor B Zhulin and Eugene V Koonin
    Citation: Genome Biology 2001 2:research0051.1
  19. The BMERC website provides a platform for searching DNA, RNA and protein sequence databases and performing bioinformatic analyses.

    Authors: Vasudeva Ginjala
    Citation: Genome Biology 2001 2:reports2018

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