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  1. Despite decades of research, the agent responsible for transmitting spongiform encephalopathies (TSEs) has not been identified. The Prion hypothesis, which dominates the field, supposes that modified host PrP ...

    Authors: Toby J Gibson
    Citation: Genome Biology 2001 2:preprint0006.1
  2. In recent years, our understanding of macromolecular transport processes across the nuclear envelope has grown dramatically, and a large number of soluble transport receptors mediating either nuclear import or...

    Authors: Anne-Christine Ström and Karsten Weis
    Citation: Genome Biology 2001 2:reviews3008.1
  3. Complete sequences of numerous mitochondrial, many prokaryotic, and several nuclear genomes are now available. These data confirm that the mitochondrial genome originated from a eubacterial (specifically α-pro...

    Authors: Michael W Gray, Gertraud Burger and B Franz Lang
    Citation: Genome Biology 2001 2:reviews1018.1
  4. The human genome contains many endogenous retroviral sequences, and these have been suggested to play important roles in a number of physiological and pathological processes. Can the draft human genome sequenc...

    Authors: David J Griffiths
    Citation: Genome Biology 2001 2:reviews1017.1
  5. As more complete genomes are sequenced, conservation of gene order between different organisms is emerging as an informative property of the genomes. Conservation of gene order has been used for predicting fun...

    Authors: Javier Tamames
    Citation: Genome Biology 2001 2:research0020.1
  6. In global gene expression profiling experiments, variation in the expression of genes of interest can often be hidden by general noise. To determine how biologically significant variation can be distinguished ...

    Authors: Agnieszka Sekowska, Stephane Robin, Jean-Jacques Daudin, Alain Henaut and Antoine Danchin
    Citation: Genome Biology 2001 2:research0019.1
  7. The mammalian olfactory apparatus is able to recognize and distinguish thousands of structurally diverse volatile chemicals. This chemosensory function is mediated by a very large family of seven-transmembrane...

    Authors: Sergey Zozulya, Fernando Echeverri and Trieu Nguyen
    Citation: Genome Biology 2001 2:research0018.1
  8. A report on the Keystone Symposium on 'Human Genetics and Genomics', Breckenridge, Colorado, USA, 31 March to 6 April, 2001.

    Authors: Anna Sharman
    Citation: Genome Biology 2001 2:reports4013.1
  9. Information for establishing the anterior-posterior axis of a mammalian embryo is contained in the fertilized egg.

    Authors: Cathy Holding
    Citation: Genome Biology 2001 2:reports0012

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