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  1. The large transforming growth factor-β (TGFβ) superfamily of secreted proteins regulate the growth, development and differentiation of cells in diverse organisms, including nematode worms, flies, mice and huma...

    Authors: Liliana Attisano and Si Tuen Lee-Hoeflich
    Citation: Genome Biology 2001 2:reviews3010.1
  2. The polarization of views on how best to exploit new information from the Human Genome Project for medicine reflects our ignorance of the genetic architecture underlying common diseases: are susceptibility all...

    Authors: Alan F Wright and Nicholas D Hastie
    Citation: Genome Biology 2001 2:comment2007.1
  3. A computational system for analysis of the repetitive structure of genomic sequences is described. The method uses suffix trees to organize and search the input sequences; this data structure has been used pre...

    Authors: Natalia Volfovsky, Brian J Haas and Steven L Salzberg
    Citation: Genome Biology 2001 2:research0027.1
  4. A report on the Cold Spring Harbor meeting on Genome Sequencing and Biology, Cold Spring Harbor, NY, USA, 9-13 May 2001.

    Authors: Martin S Taylor
    Citation: Genome Biology 2001 2:reports4018.1
  5. We propose two different formulations of the Rasch statistical models to the problem of relating gene expression profiles to the phenotypes. One formulation allows us to investigate whether a cluster of genes ...

    Authors: Hongzhe Li and Fangxin Hong
    Citation: Genome Biology 2001 2:research0031.1
  6. The DNA sequence of one of the smallest eukaryotic genomes has recently been finished - that of the reduced nucleus, or nucleomorph, of an algal endosymbiont that resides within a cryptomonad host cell. Its se...

    Authors: Paul R Gilson
    Citation: Genome Biology 2001 2:reviews1022.1
  7. is dedicated to providing information about imprinted genes for researchers, students and others interested in the subject.

    Authors: Vasudeva Ginjala
    Citation: Genome Biology 2001 2:reports2009
  8. The mfold server has a simple interface that allows any researcher to analyze a submitted RNA sequence for various secondary structures using up-to-date algorithms and free-energy rules.

    Authors: Steven G Gray
    Citation: Genome Biology 2001 2:reports2007
  9. COPE is the electronic updated version of the Dictionary of Cytokines (Wiley; New York:1994) and represents a comprehensive online reference guide to the field of cytokine research.

    Authors: Steven G Gray
    Citation: Genome Biology 2001 2:reports2006
  10. Chorismate mutases of the AroQ homology class are widespread in the Bacteria and the Archaea. Many of these exist as domains that are fused with other aromatic-pathway catalytic domains. Among the monofunction...

    Authors: David H Calhoun, Carol A Bonner, Wei Gu, Gary Xie and Roy A Jensen
    Citation: Genome Biology 2001 2:research0030.1
  11. The availability of complete genome sequences enables all the members of a gene family to be identified without limitations imposed by temporal, spatial or quantitative aspects of mRNA expression. Using the ne...

    Authors: Jodi M Maglich, Ann Sluder, Xiaojun Guan, Yunling Shi, David D McKee, Kevin Carrick, Kim Kamdar, Timothy M Willson and John T Moore
    Citation: Genome Biology 2001 2:research0029.1
  12. The Master Catalog is a collection of evolutionary families, including multiple sequence alignments, phylogenetic trees and reconstructed ancestral sequences, for all protein-sequence modules encoded by genes ...

    Authors: David A Liberles, David R Schreiber, Sridhar Govindarajan, Stephen G Chamberlin and Steven A Benner
    Citation: Genome Biology 2001 2:research0028.1
  13. A multiple copy gene family on the human Y chromosome has been shown to be transcribed but not translated.

    Authors: S Subramanian
    Citation: Genome Biology 2001 2:reports0023
  14. A novel protein upregulated in certain cancers has been identified and characterized using an integrated proteomics, genomics, bioinformatics and standard molecular biology approach.

    Authors: Steven G Gray
    Citation: Genome Biology 2001 2:reports0022
  15. Recombinant inbred (RI) strains of mice are an important resource used to map and analyze complex traits. They have proved particularly effective in multidisciplinary genetic studies. Widespread use of RI stra...

    Authors: Robert W Williams, Jing Gu, Shuhua Qi and Lu Lu
    Citation: Genome Biology 2001 2:preprint0007.1
  16. The primary sequence of Xist seems not to be important for Xist to function in X-chromosome inactivation.

    Authors: Cathy Holding
    Citation: Genome Biology 2001 2:reports0021

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