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  1. The Spt4, Spt5, and Spt6 proteins are conserved eukaryotic transcription-elongation factors. Recent studies have provided the first evidence that they are generally required in multicellular eukaryotes, includ...

    Authors: Fred Winston

    Citation: Genome Biology 2001 2:reviews1006.1

    Content type: Minireview

    Published on:

  2. Programmed DNA-reorganization and DNA-elimination events take place frequently during cellular differentiation. An extreme form of such processes, involving DNA reorganization, DNA elimination and DNA fragment...

    Authors: Franziska Jönsson, Günther Steinbrück and Hans J Lipps

    Citation: Genome Biology 2001 2:research0005.1

    Content type: Research

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  3. We have developed and tested a method for printing protein microarrays and using these microarrays in a comparative fluorescence assay to measure the abundance of many specific proteins in complex solutions. A...

    Authors: Brian B Haab, Maitreya J Dunham and Patrick O Brown

    Citation: Genome Biology 2001 2:research0004.1

    Content type: Research

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  4. Replicative DNA polymerases are essential for the replication of the genomes of all living organisms. On the basis of sequence similarities they can be classified into three types. Type A polymerases are homol...

    Authors: M Mar Albà

    Citation: Genome Biology 2001 2:reviews3002.1

    Content type: Protein family review

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  5. We propose a new method for supervised learning from gene expression data. We call it 'tree harvesting'. This technique starts with a hierarchical clustering of genes, then models the outcome variable as a sum...

    Authors: Trevor Hastie, Robert Tibshirani, David Botstein and Patrick Brown

    Citation: Genome Biology 2001 2:research0003.1

    Content type: Research

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  6. Ring-type polymerases consist of a DNA polymerase, a ring-shaped sliding clamp protein and a clamp-loading complex. Sliding clamp proteins are found in all organisms and are called proliferating cell nuclear a...

    Authors: Irina Bruck and Mike O'Donnell

    Citation: Genome Biology 2001 2:reviews3001.1

    Content type: Protein family review

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  7. The mechanism by which the plant reserves some cells as pluripotent stem cells while partitioning others into differentiated leaf tissue is fundamental to plant development. New work in Arabidopsis elucidates the...

    Authors: M Kathryn Barton

    Citation: Genome Biology 2001 2:reviews1002.1

    Content type: Minireview

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  8. To assess how automatic function assignment will contribute to genome annotation in the next five years, we have performed an analysis of 31 available genome sequences. An emerging pattern is that function can...

    Authors: Ioannis Iliopoulos, Sophia Tsoka, Miguel A Andrade, Paul Janssen, Benjamin Audit, Anna Tramontano, Alfonso Valencia, Christophe Leroy, Chris Sander and Christos A Ouzounis

    Citation: Genome Biology 2000 2:interactions0001.1

    Content type: Open letter

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  9. The Ensembl software automatically produces and archives annotation of the draft human genome sequence.

    Authors: Colin Semple

    Citation: Genome Biology 2000 2:reports2001

    Content type: Web report

    Published on:

  10. Three major defense signaling molecules have been shown to trigger partly overlapping gene expression profiles in Arabidopsis.

    Authors: Thomas Eulgem

    Citation: Genome Biology 2000 2:reports0001

    Content type: Paper report

    Published on:

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