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  1. A report from HGM2001, the sixth annual International Human Genome Meeting organized by The Human Genome Organisation (HUGO), Edinburgh, UK, 19-22 April 2001.

    Authors: Colin AM Semple, Martin S Taylor and Stephane Ballereau
    Citation: Genome Biology 2001 2:reports4015.1
  2. The ExPASy proteomics server is a dedicated site for the analysis of protein sequences, protein structures and two-dimensional polyacrylamide gel electrophoresis.

    Authors: David Chambers
    Citation: Genome Biology 2001 2:reports2004
  3. Immotile cilia syndrome (ICS) or primary ciliary dyskinesia (PCD) is an autosomal recessive disorder in humans in which the beating of cilia and sperm flagella is impaired. Ciliated epithelial cell linings are...

    Authors: Amit K Maiti, Mark Jorissen and Patrice Bouvagnet
    Citation: Genome Biology 2001 2:research0026.1
  4. A novel in silico method based on comparative and physicochemical considerations can help to predict the impact of amino-acid replacement on protein structure and function.

    Authors: Reiner Veitia
    Citation: Genome Biology 2001 2:reports0020
  5. An in silico approach has been used to sort the effects on protein structure or function of amino-acid substitutions at conserved compared to non-conserved sites.

    Authors: Reiner Veitia
    Citation: Genome Biology 2001 2:reports0019
  6. The SRY gene has been shown to be a direct transcriptional target of the WT1 transcription factor.

    Authors: Cathy Holding
    Citation: Genome Biology 2001 2:reports0018
  7. The development and activation of CD4+ helper T cell (Th) subsets with distinct patterns of unbalanced production of cytokines play an important part in infectious, allergic and autoimmune diseases. Human neonata...

    Authors: Heli Hamalainen, Hua Zhou, William Chou, Hideki Hashizume, Renu Heller and Riitta Lahesmaa
    Citation: Genome Biology 2001 2:research0022.1
  8. Authors: Jonathan B Weitzman
    Citation: Genome Biology 2001 2:spotlight-20010613-02
  9. Techniques commonly applied to the discovery of unknown prokaryotes have now been used to identify new eukaryotic lineages within picoplankton.

    Authors: James Cotton
    Citation: Genome Biology 2001 2:reports0016
  10. Despite decades of research, the agent responsible for transmitting spongiform encephalopathies (TSEs) has not been identified. The Prion hypothesis, which dominates the field, supposes that modified host PrP ...

    Authors: Toby J Gibson
    Citation: Genome Biology 2001 2:preprint0006.1
  11. In recent years, our understanding of macromolecular transport processes across the nuclear envelope has grown dramatically, and a large number of soluble transport receptors mediating either nuclear import or...

    Authors: Anne-Christine Ström and Karsten Weis
    Citation: Genome Biology 2001 2:reviews3008.1
  12. Complete sequences of numerous mitochondrial, many prokaryotic, and several nuclear genomes are now available. These data confirm that the mitochondrial genome originated from a eubacterial (specifically α-pro...

    Authors: Michael W Gray, Gertraud Burger and B Franz Lang
    Citation: Genome Biology 2001 2:reviews1018.1
  13. The human genome contains many endogenous retroviral sequences, and these have been suggested to play important roles in a number of physiological and pathological processes. Can the draft human genome sequenc...

    Authors: David J Griffiths
    Citation: Genome Biology 2001 2:reviews1017.1
  14. As more complete genomes are sequenced, conservation of gene order between different organisms is emerging as an informative property of the genomes. Conservation of gene order has been used for predicting fun...

    Authors: Javier Tamames
    Citation: Genome Biology 2001 2:research0020.1
  15. In global gene expression profiling experiments, variation in the expression of genes of interest can often be hidden by general noise. To determine how biologically significant variation can be distinguished ...

    Authors: Agnieszka Sekowska, Stephane Robin, Jean-Jacques Daudin, Alain Henaut and Antoine Danchin
    Citation: Genome Biology 2001 2:research0019.1
  16. The mammalian olfactory apparatus is able to recognize and distinguish thousands of structurally diverse volatile chemicals. This chemosensory function is mediated by a very large family of seven-transmembrane...

    Authors: Sergey Zozulya, Fernando Echeverri and Trieu Nguyen
    Citation: Genome Biology 2001 2:research0018.1

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