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  1. Chorismate mutases of the AroQ homology class are widespread in the Bacteria and the Archaea. Many of these exist as domains that are fused with other aromatic-pathway catalytic domains. Among the monofunction...

    Authors: David H Calhoun, Carol A Bonner, Wei Gu, Gary Xie and Roy A Jensen
    Citation: Genome Biology 2001 2:research0030.1
  2. The availability of complete genome sequences enables all the members of a gene family to be identified without limitations imposed by temporal, spatial or quantitative aspects of mRNA expression. Using the ne...

    Authors: Jodi M Maglich, Ann Sluder, Xiaojun Guan, Yunling Shi, David D McKee, Kevin Carrick, Kim Kamdar, Timothy M Willson and John T Moore
    Citation: Genome Biology 2001 2:research0029.1
  3. The Master Catalog is a collection of evolutionary families, including multiple sequence alignments, phylogenetic trees and reconstructed ancestral sequences, for all protein-sequence modules encoded by genes ...

    Authors: David A Liberles, David R Schreiber, Sridhar Govindarajan, Stephen G Chamberlin and Steven A Benner
    Citation: Genome Biology 2001 2:research0028.1
  4. A multiple copy gene family on the human Y chromosome has been shown to be transcribed but not translated.

    Authors: S Subramanian
    Citation: Genome Biology 2001 2:reports0023
  5. A novel protein upregulated in certain cancers has been identified and characterized using an integrated proteomics, genomics, bioinformatics and standard molecular biology approach.

    Authors: Steven G Gray
    Citation: Genome Biology 2001 2:reports0022
  6. Recombinant inbred (RI) strains of mice are an important resource used to map and analyze complex traits. They have proved particularly effective in multidisciplinary genetic studies. Widespread use of RI stra...

    Authors: Robert W Williams, Jing Gu, Shuhua Qi and Lu Lu
    Citation: Genome Biology 2001 2:preprint0007.1
  7. The primary sequence of Xist seems not to be important for Xist to function in X-chromosome inactivation.

    Authors: Cathy Holding
    Citation: Genome Biology 2001 2:reports0021
  8. In most eukaryotes, histones, which are the major structural components of chromatin, are expressed as a family of sequence variants encoded by multiple genes. Because different histone variants can contribute...

    Authors: David T Brown
    Citation: Genome Biology 2001 2:reviews0006.1
  9. The recent draft assembly of the human genome provides a unified basis for describing genomic structure and function. The draft is sufficiently accurate to provide useful annotation, enabling direct observatio...

    Authors: Fred A Wright, William J Lemon, Wei D Zhao, Russell Sears, Degen Zhuo, Jian-Ping Wang, Hee-Yung Yang, Troy Baer, Don Stredney, Joe Spitzner, Al Stutz, Ralf Krahe and Bo Yuan
    Citation: Genome Biology 2001 2:research0025.1
  10. A report on Novartis Foundation Symposium 244 "The Genetics and Biology of Sex Determination", London, UK, 1-3 May 2001.

    Authors: Andrew Sinclair
    Citation: Genome Biology 2001 2:reports4017.1
  11. The evolutionary history of eukaryotic proteins involves rapid sequence divergence, addition and deletion of domains, and fusion and fission of genes. Although the protein repertoires of distantly related spec...

    Authors: Chris P Ponting and Nicholas J Dickens
    Citation: Genome Biology 2001 2:comment2006.1
  12. Two recent reports describe mRNA and protein expression patterns in the bacterium Caulobacter crescentus. The combined use of DNA microarray and proteomic analyses provides a powerful new perspective for unraveli...

    Authors: Jean D Amick and Yves V Brun
    Citation: Genome Biology 2001 2:reviews1020.1
  13. Microarrays of mouse genes are now available from several sources, and they have so far given new insights into gene expression in embryonic development, regions of the brain and during apoptosis. Microarray d...

    Authors: Dennis A Wigle, Janet Rossant and Igor Jurisica
    Citation: Genome Biology 2001 2:reviews1019.1
  14. A report on the second European conference on zebrafish genetics and development. University College, London, 19-22 April 2001.

    Authors: David Bassett
    Citation: Genome Biology 2001 2:reports4016.1
  15. A report from HGM2001, the sixth annual International Human Genome Meeting organized by The Human Genome Organisation (HUGO), Edinburgh, UK, 19-22 April 2001.

    Authors: Colin AM Semple, Martin S Taylor and Stephane Ballereau
    Citation: Genome Biology 2001 2:reports4015.1
  16. The ExPASy proteomics server is a dedicated site for the analysis of protein sequences, protein structures and two-dimensional polyacrylamide gel electrophoresis.

    Authors: David Chambers
    Citation: Genome Biology 2001 2:reports2004

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