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  1. Content type: Meeting report

    A report from the "Quantitative challenges in the post-genomic sequence era" workshop and symposium, San Diego, January 11-15, 2000

    Authors: Gregory A Petsko

    Citation: Genome Biology 2000 1:reports406.1

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  2. Content type: Meeting report

    A report from the minisymposium on regulated secretion at the 39th Annual Meeting of the American Society for Cell Bilogy, Washington DC, December 11-15, 1999

    Authors: Colin Jamora

    Citation: Genome Biology 2000 1:reports402.1

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  3. Content type: Web report

    Launched in September 1998, dbSNP is the central repository for data on single-nucleotide polymorphisms (SNPs), the most common form of sequence variation in human populations.

    Authors: Colin Semple

    Citation: Genome Biology 2000 1:reports243

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  4. Content type: Web report

    Given the variety of codon usage by different organisms and organelles, this centralized codon-usage resource is invaluable.

    Authors: Todd Richmond

    Citation: Genome Biology 2000 1:reports241

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  5. Content type: Web report

    The unified database (UDB) attempts to create an integrated map based on human genome mapping data retrieved from a number of public databases.

    Authors: Kathryn Evans

    Citation: Genome Biology 2000 1:reports238

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  6. Content type: Web report

    Finding the relevant database is not always easy, and for some years Nucleic Acids Research has dedicated its first issue of the year to information about the most important existing databases.

    Authors: Mar Albà

    Citation: Genome Biology 2000 1:reports235

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  7. Content type: Minireview

    The availability of complete genomic sequences of Saccharomyces cerevisiae has catalyzed a cultural change in the practice of yeast biology, providing opportunities to develop high throughput techniques to define...

    Authors: Charles Brenner

    Citation: Genome Biology 2000 1:reviews103.1

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  8. Content type: Minireview

    For those working on the actin cytoskeleton, a major theme of the 39th annual meeting of the American Society for Cell Biology [

    Authors: Anne Ridley

    Citation: Genome Biology 2000 1:reviews102.1

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  9. Content type: Minireview

    The key molecules involved in regulating the assembly and function of the mitotic spindle are shared by evolutionarily divergent species. Studies in different model systems are leading to convergent conclusion...

    Authors: Claire E Walczak

    Citation: Genome Biology 2000 1:reviews101.1

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  10. Content type: Paper report

    GeneCalling, a new expression profiling technique, has been used to elucidate regulatory gene networks in plants.

    Authors: Leonore Reiser

    Citation: Genome Biology 2000 1:reports034

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  11. Content type: Paper report

    Serial analysis of gene expression (SAGE) has been used to analyze the complete human 'transcriptome' - the number, identity and level of expression of genes in humans.

    Authors: Hamish Scott

    Citation: Genome Biology 2000 1:reports031

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  12. Content type: Paper report

    Members of the Arabidopsis Genome Initiative, including the European Union Arabidopsis Genome Sequencing Consortium and The Cold Spring Harbor, Washington University in St Louis and PE Biosystems Arabidopsis Sequ...

    Authors: Todd Richmond

    Citation: Genome Biology 2000 1:reports030

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  13. Content type: Paper report

    Members of the Arabidopsis Genome Initiative, primarily from The Institute for Genomic Research, have completed sequencing one of the first two plant chromosomes.

    Authors: Todd Richmond

    Citation: Genome Biology 2000 1:reports029

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  14. Content type: Paper report

    Mouse chromosomes carrying deletions have been produced using a combination of targeted and random integration of selectable markers followed by specific excision by a recombinase.

    Authors: Paul Denny

    Citation: Genome Biology 2000 1:reports027

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  15. Content type: Paper report

    PCR screening five collections of mutagenized Arabidopsis lines to find those that have T-DNA or transposon insertions in 73 members of the R2R3 MYB gene family has identified 47 insertions into 36 genes.

    Authors: Seung Yon Rhee

    Citation: Genome Biology 2000 1:reports025

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  16. Content type: Paper report

    A new noninvasive technique has been developed that successfully measures calcium dynamics in single Arabidopsis guard cells.

    Authors: Kath Carr and Alistair Hetherington

    Citation: Genome Biology 2000 1:reports024

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  17. Content type: Paper report

    The crystal structure of human SRP54M from the signal recognition particle (SRP) reveals a homodimer interaction, which may be a model for the way signal sequences on nascent proteins recognize and activate th...

    Authors: Rachel Brem

    Citation: Genome Biology 2000 1:reports020

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  18. Content type: Paper report

    Systems analysis of the complete genome sequence combined with biochemical information on metabolic pathways has been used to define and elucidate the relationship between genotype and phenotype for Haemophilus i...

    Authors: Mary Wildermuth

    Citation: Genome Biology 2000 1:reports016

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  19. Content type: Paper report

    Correlation-based clustering of plant expressed sequence tags allows conclusions to be drawn about the relationship between genes based on their expression patterns in different tissues.

    Authors: Philippe Reymond

    Citation: Genome Biology 2000 1:reports010

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  20. Content type: Research

    Differences in responses to bacterial surface lipopolysaccharides (LPSs) are apparent between and within mammalian species. It has been shown in mice that resistance to LPS is caused by defects in the Toll-lik...

    Authors: Irina Smirnova, Alexander Poltorak, Edward KL Chan, Colleen McBride and Bruce Beutler

    Citation: Genome Biology 2000 1:research002.1

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  21. Content type: Research

    The formin family of proteins has been implicated in signaling pathways of cellular morphogenesis in both animals and fungi; in the latter case, at least, they participate in communication between the actin cy...

    Authors: Fatima Cvrcková

    Citation: Genome Biology 2000 1:research001.1

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  22. Content type: Paper report

    The use of cDNA microarrays for the study and mapping of gene amplifications and deletions on a whole-genome scale provides a comparison of DNA copy numbers in normal and tumor cells at unprecedented resolution.

    Authors: Aude Fahrer

    Citation: Genome Biology 2000 1:reports011

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  23. Content type: Web report

    This site has a collection of features dealing with different areas of genetic research, and is an interesting and useful piece of 'popular science'.

    Authors: Basil Safwat

    Citation: Genome Biology 2000 1:reports213

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  24. Content type: Web report

    This comprehensive online biology reference book consists of lists of terms covering an extensive range of biological topics, and is aimed primarily at graduate students.

    Authors: Ines Chyla

    Citation: Genome Biology 2000 1:reports207

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  25. Content type: Web report

    SYFPEITHI, a database of interactions between proteins of the major histocompatibility complex (MHC) and antigenic peptides, contains information on MHC-associated peptide sequences, anchor positions, MHC mole...

    Authors: Christopher J Thorpe

    Citation: Genome Biology 2000 1:reports203

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  26. Content type: Paper report

    YopJ, a virulence factor of Yersinia pseudotuberculosis, can bind to several key intracellular signaling proteins, members of the MAPKK family, preventing their activation and protecting the pathogen from host de...

    Authors: Jonathan B Weitzman

    Citation: Genome Biology 2000 1:reports001

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