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Fig. 5 | Genome Biology

Fig. 5

From: Phenome-wide analyses identify an association between the parent-of-origin effects dependent methylome and the rate of aging in humans

Fig. 5

The 92 high-confidence associations between POE-CpGs and phenotypes. Red circles: phenotypic categories. Yellow circles: POE-CpGs. Dotted grey ovals: POE-CpGs located within the same gene are grouped in the same oval. Gene names with purple background: the POE-CpGs within that gene were associated with phenotypes from multiple trait categories. Lines: each line represents a significant pair, with red and blue lines representing negative and positive correlations, respectively; the two red dotted lines mark that, although the associations between cg18092474 and cg19089201 with mother’s lifespan reached statistical significance, they were likely introduced by the association between maternal smoking and mother’s lifespan

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