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Fig. 3 | Genome Biology

Fig. 3

From: m6A readers ECT2/ECT3/ECT4 enhance mRNA stability through direct recruitment of the poly(A) binding proteins in Arabidopsis

Fig. 3

ECT2/ECT3/ECT4 promote stabilization of target m6A-modified mRNA. a–b Cumulative distribution of relative mRNA expression in ect2-1 compared to WT (a) and ect2/3/4 compared to WT (b) for Non-targets (black), ECT2 targets (blue), and ECT2 & m6A targets (red). c Cumulative distribution of mRNA half-life in WT for Non-targets (black), ECT2 targets (blue), and ECT2 & m6A targets (red). d Cumulative distribution of mRNA half-life in WT, analyzed based on the number of ECT2 target sites in each transcript. e Cumulative distribution of relative mRNA half-life log2 fold changes between ect2/3/4 and WT for Non-targets (black), ECT2 targets (blue), and ECT2 & m6A targets (red). f Cumulative distribution of mRNA half-life log2 fold changes between ect2/3/4 and WT, analyzed based on the number of ECT2 target sites in each transcript. P-values were calculated using two-sided Mann–Whitney U test

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