Fig. 6From: Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cellsAmplicon sequencing confirms no indel formation at base-edited sites when combining Cas12a nuclease and Cas9 BE. Summary of CRIPResso2 analysis showing the frequency of total modified reads, frequency of indels, and quantification of intended base editing-mediated base changes mapped to B2M (a) or to CIITA (b). n = 5 healthy donorsBack to article page