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Fig. 4 | Genome Biology

Fig. 4

From: A graph neural network-based interpretable framework reveals a novel DNA fragility–associated chromatin structural unit

Fig. 4

Neck interactions at DSB sites are biologically distinct from those at non-DSB sites. a Neck interactions at DSB sites (dashed line with red dot) are more likely to be loops than those at non-DSB sites (dashed line with blue dot). b Example that the neck interaction of DSB site is a loop, of which the left anchor is the DSB site and the right anchor is a neck neighbor of DSB site. c Neck neighbors of DSB sites are more enriched in region of CDS and UTR, compared with those of non-DSB sites. d Neck neighbors of DSB sites are more likely to be DSBs. e Neck neighbors of DSB sites are more enriched with CTCF and DNase I signals than those of non-DSBs

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