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Table 1 Methodologies of imputation methods. The table lists the modeling strategies and input features used by each of the models, as reported by the teams. The models include k-nearest neighbors (KNN), deep tensor factorization (DTF), autoencoders (AE), convolutional neural networks (CNN), hidden Markov models (HMM), and gradient-boosted decision trees (GBT). The authors of Aug2019Impute and CostaLab v2 did not describe their methods

From: The ENCODE Imputation Challenge: a critical assessment of methods for cross-cell type imputation of epigenomic profiles

Name

Model

Norm

Inputs

Sequence

Functional

Average

Avocado

Aug2019Impute

      

BrokenNodes/v2

KNN

arcsinh

 

\(\checkmark\)

  

BrokenNodes v3

KNN

arcsinh

 

\(\checkmark\)

 

\(\checkmark\)

CostaLab v2

      

CUImpute1/CUWA/ICU

ensemble

arcsinh

 

\(\checkmark\)

\(\checkmark\)

\(\checkmark\)

Guacamole/Lavawizard

DTF

arcsinh

 

\(\checkmark\)

\(\checkmark\)

 

HLYG/v1/v2

GBT

quantile

\(\checkmark\)

\(\checkmark\)

\(\checkmark\)

 

imp/imp1

DTF+AE

Cauchy

 

\(\checkmark\)

  

KKT-ENCODE

CNN

arcsinh

\(\checkmark\)

   

LiPingChun

DTF

arcsinh

 

\(\checkmark\)

\(\checkmark\)

 

NittanyLions

KNN

  

\(\checkmark\)

  

NittanyLions2

KNN

quantile

 

\(\checkmark\)

  

SongLab

CNN

log1p

 

\(\checkmark\)

  

SongLab2

HMM

  

\(\checkmark\)

  

SongLab3

CNN

log1p

 

\(\checkmark\)

\(\checkmark\)

\(\checkmark\)

UIOWA

CNN

quantile

\(\checkmark\)

\(\checkmark\)