Fig. 3

Additional performance measures. A Experimentally observed signal for H3K27ac in brain microvascular endothelial cells. B An example of partitioning the track from A into logarithmically spaced bins (the rows). C The accuracy between binarized imputations and MACS2 peak calls for each signal bin when using the experimental signal to define the bins. D The same as C except using the imputed signal to define the bins. E The same as A but a different locus. F The same as B except calculating bins using the number of cell types that each locus exhibits a peak in. G The precision of the binarized imputed signal against MACS2 peak calls when evaluated separately for each bin. H The same as G except the recall instead of the precision. I The average area under the curves, calculated as shown in C, across all test set tracks for each participant. J The average area under the curves calculated as shown in D across all test set tracks for each participant. K The precision score calculated in the same manner as I/J. L The same as K, except the recall score. M The average H3K4me3 profile of experimental (blue), quantile-normalized (magenta), and imputed signals at strand-corrected promoters. N The average Pearson correlation between imputed and quantile-normalized signal across all promoters and H3K4me3 test set tracks. O The average Pearson correlation between imputed and quantile-normalized signal across all observed DNase peaks and DNase test set tracks