Fig. 4

Four newly identified TSNGs in the top 10 signals. A–D The regional plots of CMS scores and recombination rates, in which the peaks indicate the selective signals. The peak SNVs are marked with colors. The results of sliding window Fay and Wu’s H tests of the four genes are also presented. A The TMEM132C gene region. B The ATP13A3 gene region. C The SANBR gene region. D The KHDRBS2 gene region. The calculated recombination rates (r²) indicate the estimated linkage disequilibrium (LD) degree between the peak SNV and the other SNVs and are coded in colors. The significance threshold of CMS = 7.66 (top 1‰) is denoted by the red dashed line. The H values refer to the maximum scores of the given regions (marked in red), covering the upstream and downstream 500-kb regions of the peak SNVs of the four genes