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Fig. 5 | Genome Biology

Fig. 5

From: FIPRESCI: droplet microfluidics based combinatorial indexing for massive-scale 5′-end single-cell RNA sequencing

Fig. 5

FIPRESCI is compatible with single-cell immune repertoire profiling. a UMAP shows the top 4 V genes usages in TRB. b Bar plots show the number of cells detected TCR VDJ by cell types (4,983). c Box plots showing the TCR clonal diversity. Diversity is calculated using Shannon metrics. d The histogram shows the distribution of the unique TCR clonotypes of the CD8 naïve (upper) and Treg (lower) across 14 donors. e Histogram showing the frequency and distribution of occupied TCR clonotypes across 14 donors. f Chord diagrams show the number of relative TCR clonotypes and the shared clonotypes across T cells in individual donors. g Box plot showing five Treg subpopulations clonotype diversity. Clonotype diversity is calculated as the Shannon index, inverse Simpson index, or Chao index within one Treg subpopulation

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Genome Biology

ISSN: 1474-760X

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