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Fig. 1 | Genome Biology

Fig. 1

From: DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology

Fig. 1

Generation of programmed mutational, deletional, and insertional libraries with DIMPLE in the model potassium channel Kir2.1. A Schematic depiction of the library generation process with DIMPLE. B Bar plot of mutation type per position against counts. All variants are stacked. Dashed lines indicate the boundaries of each mutagenic sublibrary. Overall, each mutagenized sublibrary region is within 2-fold of each other, indicating well-balanced libraries (Additional file 3: Fig S3B)

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