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Fig. 7 | Genome Biology

Fig. 7

From: SRTsim: spatial pattern preserving simulations for spatially resolved transcriptomics

Fig. 7

Benchmarking cell-cell communication identification methods using synthetic data from SRTsim. A The power of different methods for identifying cell-cell communications is measured by mean F1 scores across a range of adjusted p-value thresholds in the heterogeneous expression settings. Compared methods include CellphoneDBv3 with spatial information (green dash line), CellphoneDBv3 without spatial information (yellow dash line), Giotto with spatial information (pink dash line), and Giotto without spatial information (blue dash line). Results are shown for four different scenarios (columns) with different cell-cell communication strength (rows). B The power of different methods for identifying cell-cell communications is measured by mean F1 scores across a range of adjusted p-value thresholds in the homogeneous expression settings. Results are again shown for four different scenarios (columns) with different cell-cell communication strengths (rows). Each setting includes 10 simulation replicates

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