Fig. 2
From: The Network Zoo: a multilingual package for the inference and analysis of gene regulatory networks
Modeling regulatory processes in melanoma using CCLE data. A Volcano plot of the ANOVA associations between TF targeting scores and promoter methylation and copy number statuses in melanoma cell lines. The 10 largest significant associations are colored in red and cyan for methylation status, and in orange and purple for copy number status. B Elastic net regression of regorafenib cell viability on TF targeting scores in melanoma cell lines. The figure represents the two largest positive coefficients and two largest negative coefficients. C Differential TF involvement in the transition between primary melanoma cell line and a cell line derived from melanoma metastasis. The top 50 TFs are colored in blue