Fig. 3
From: The genetic and evolutionary basis of gene expression variation in East Africans
Fine-mapping in East Africans vs. GTEx v8. A Credible set (CS) sizes for eGenes identified in 162 East Africans (Afr) or a subset of 162 European Americans from GTEx v8 (EA162). B Locus plot of NR1D1 eQTLs identified in 162 East Africans (Afr) or the full GTEx v8 cohort (v8). P-values are overlaid with African (YRI) and European American (CEU) recombination rates, GENCODE v19 [40] gene models from the UCSC genome browser [41] (http://genome.ucsc.edu) and inferred ChromHMM [42] states for GM12878 [43]. The top SNP in Africans, rs883871, disrupts a nucleotide for the core motif of ETS family transcription factors (motif of ETS1 shown)