From: Conservation and divergence of canonical and non-canonical imprinting in murids
Gene | Full name | Chr. | EPC-DMR (Overlapping LTR-LTR family) | Putative mechanism underlying specie-specific imprinting | Gene ontology (process) | Note |
---|---|---|---|---|---|---|
Gsto1 | Glutathione S-Transferase Omega 1 | chr1 | N.I. | Unknown | Glutathione metabolic process | |
Zfp64 | Zinc finger protein 64 | chr3 | Mat | Oocyte epigenome (DNAme vs H3K27me3) | Mesenchymal cell differentiation | |
LOC108350526 | chr3 | Mat (RMER13A/RLTR20B3-ERVK) | Oocyte epigenome (DNAme vs H3K27me3) | Unknown | Â | |
Syt16AS (LOC102550910) | Synaptotagmin 16 - antisense | chr6 | Mat (MTC-ERVL) | Unknown | Exocytosis (Syt16) | |
Gadl1-3'UTR | Glutamate Decarboxylase Like 1 | chr8 | Mat (RMER3B-ERVK) | Unknown | Carboxylic acid metabolic process (Gadl1) | |
Slc38a1 | Solute Carrier Family 38 Member 1 | chr7 | Mat (RMER6B/ORR1A4/MTD-ERVK/ERVL) | LTR insertion and ZFP57 motifs | Amino acid transmembrane transport | |
Rpl39l | Ribosomal Protein L39 Like | chr10 | Mat | Unknown | Unknown | Â |
Sfmbt2 | Scm like with four mbt domains 2 | chr17 | Mat | Common imprinting between rats and mice | Negative regulation of gene expression | Sfmbt2 is essential for trophoblast maintenance and placenta development in mice [84, 85]. |
Zfp516 | Zinc finger protein 516 | chr18 | Mat | Oocyte epigenome (DNAme vs H3K27me3) | Brown fat cell differentiation | |
Sall1 | Spalt Like Transcription Factor 1 | chr19 | Mat (RLTR20B3-ERVK) | Common imprinting between rats and mice | Heart/kidney/limb development | |
Gab1 | GRB2 Associated Binding Protein 1 | chr19 | Mat (RLTR15-ERVK) | Common imprinting between rats and mice | MAPK cascade/Angiogenesis | Gab1 is essential for development of placenta (syncytiotrophoblast) in mice [20]. |