Conservation and divergence of canonical and non-canonical imprinting in murids

Table 1 List of canonically imprinted genes identified in the rat and mouse

Genomic loci	Chr.	gDMR	Epi-DMR	EPC-DMR	Identified imprinted genes	DMR type in mice	Imprinting in non-rodent mammals^c
H19-Igf2	1	Pat	Pat	Pat	Igf2, H19	Pat	Human, cow, pig, opossum, wallaby
Dlk1-Meg3	6	Pat	N.I.	N.I.	Rtl1AS, Meg3, miRNA cluster	Pat	Human, cow, pig
Rasgrf1	8	Pat	Pat	Pat	Rasgrf1^b	Pat	Pig
Peg3	1	Mat	Mat	Mat	Peg3^b	Mat	Human, cow, pig
Snrpn	1	Mat	Mat	Mat	Snrpn, Snurf, Magel2	Mat	Human, cow, pig
Inpp5f	1	Mat	N.I.	N.I.		Mat	Human, cow, pig
Kcnq1ot1^a	1	Mat	N.I.	N.I.	Kcnq1ot1, Trpm5, Tssc4, Ascl2, Cd81	Mat	Human, cow, pig
Airn-Igf2r	1	Mat	N.I.	N.I.	Igf2r^b	Mat	Human, cow, pig, opossum, wallaby
Plagl1	1	Mat	Mat	Mat		Mat	Human, cow, pig
Mcts2	3	Mat	N.I.	N.I.		Mat	Human
Nnat	3	Mat	N.I.	N.I.		Mat	Human, cow, pig
Gnas (Nespas-GnasXL)	3	Mat	N.I.	N.I.	Gnas	Mat	Human, cow, pig
Gnas (exon 1A)	3	Mat	Mat	Mat	Gnas	Mat	Human
Sgce-Peg10	4	Mat	Mat	Mat	Sgce, Peg10	Mat	Human, cow, pig, wallaby
Mest	4	Mat	Mat	Mat		Mat	Human, cow, opossum, wallaby
Nap1l5	4	Mat	N.I.	N.I.		Mat	Human, cow, pig
Trappc9	7	Mat	Mat	Mat		Mat	Human
Slc38a4	7	Mat	N.I.	N.I.	Slc38a4	Mat	Pig
Zdbf2	9	Mat	N.I.	N.I.	Zdbf2	Mat (transient)	Human
Fkbp6	12	Mat	N.I.	N.I.		Mat
Grb10	14	Mat	Mat	Mat	Grb10	Mat	Human
Zrsr1	14	Mat	Mat	Mat	Zrsr1	Mat
Impact	18	Mat	Mat	Mat	Impact^b	Mat	Cow
Cdh15	19	Mat	N.I.	Mat		Mat (transient)

Pat Paternally methylated, Mat Maternally methylated, N.I. Not informative
^aNot annotated in rat
^bThese genes are reported to be imprinted (expressed) in rats in previous studies [11]
^cOne or more genes in the orthologous imprinted cluster have been reported to be imprinted in human, cow (and pig), or marsupials [11, 35, 37,38,39,40,41,42,43,44]

ISSN: 1474-760X