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Fig. 3 | Genome Biology

Fig. 3

From: REPAC: analysis of alternative polyadenylation from RNA-sequencing data

Fig. 3

3′-UTR-shortening events in naive and LPS-activated B cells. A Differences in 3′-UTR coverage of secretion associated genes Cd47 and Edem1. The coverage was normalized by the highest expressing base pair. B Heatmap showing the relationship between the usage of the proximal and distal PAS (PPAS:DPAS) and expression levels (CPM) using standardized values. Overall, preferential usage of the shorter 3′-UTR isoform (blue color) is associated with higher expression levels (red color) for the genes involved in secretion and IFN-I response

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