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Fig. 5 | Genome Biology

Fig. 5

From: BIGKnock: fine-mapping gene-based associations via knockoff analysis of biobank-scale data

Fig. 5

Putative causal genes at selected loci for UK Biobank binary traits. Scatter plots of W knockoff statistics (BIGKnock) vs. \(-\text {log}_{10}\)(p value) (GeneScan3D) for selected loci of a asthma, b–c type 2 diabetes (T2D), d–e hypothyroidism, and f–g hyperlipidemia. Loci are named according to the most significant gene in BIGKnock. The dashed lines show the significance thresholds defined by Bonferroni correction (for p-values) and by false discovery rate (FDR; for W statistic).

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