Fig. 1
From: BIGKnock: fine-mapping gene-based associations via knockoff analysis of biobank-scale data
Power, FDR and computing time comparisons for different methods. a and b Power and FDR comparisons between GeneScan3D-BH, GeneScan3DKnock and BIGKnock (M=5 knockoffs) for continuous and binary traits. c Computing time for different methods to generate knockoffs: GeneScan3DKnock and BIGKnock (with shrinkage algorithmic leveraging). The computing time were evaluated based on a gene with 1347 variants, varying the sample size from 1000 to 400,000