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Fig. 6 | Genome Biology

Fig. 6

From: CeDAR: incorporating cell type hierarchy improves cell type-specific differential analyses in bulk omics data

Fig. 6

Accuracy of detecting csDM in human whole blood methylation data. The human blood DNA methylation dataset (GEO accession number: GSE166844) contains both bulk samples from whole blood and pure cell type samples of granulocytes, CD8, CD4, monocytes, and B cells derived by FACS. The csDM sites associated with sex were identified between eighteen females and twelve males samples using TOAST, TCA, csSAM, CellDMC, CeDAR-S, and CeDAR-M. The results are evaluated by TDR curves. The estimated proportions and estimated tree structure of cell types are shown in the last panel

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