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Fig. 5 | Genome Biology

Fig. 5

From: CeDAR: incorporating cell type hierarchy improves cell type-specific differential analyses in bulk omics data

Fig. 5

Accuracy of detecting csDM in human brain methylation data. The human brain DNA methylation dataset (GEO accession number: GSE41826) contains both bulk samples from postmortem frontal cortex and matched cell type samples of neuron and glia purified by fluorescence-activated cell sorting (FACS). The csDM sites associated with sex were identified between five healthy male and five healthy female samples with TOAST, TCA, csSAM, CellDMC, and CeDAR-S. The results are evaluated by the true discovery rate (TDR) curves, which show the accuracy among different numbers of top-ranked csDM sites from each method.

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Genome Biology

ISSN: 1474-760X

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