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Fig. 7 | Genome Biology

Fig. 7

From: An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

Fig. 7

Model of T1- and T2-LADs. Data from the atlas shows T1-LADs have greater LB1 contact frequency (CF) and H3K9me2 enrichment, lower transcription, lower overall accessibility, lower gene density, and greater localization with the layer of peripheral LB1 compared to T2-LADs. This suggests that T2-LADs are a peripheral chromatin subtype localized to an intermediate layer of chromatin at the nuclear periphery that borders nonLADs

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Genome Biology

ISSN: 1474-760X

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