Fig. 1From: Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approachesa Genome-wide off-target prediction methods can be classified into three different categories: cell-based, in vitro, and in silico. b Schematic of the Extru-seq method. c Hypothesis about the dual properties of Extru-seq, which shares characteristics with cell-based and in vitro methodsBack to article page